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肝脏子宫内膜异位症:1例罕见病例及文献复习

Hepatic endometriosis: a rare case and review of the literature.

作者信息

Liu Kai, Zhang Wei, Liu Songyang, Dong Bingfei, Liu Yahui

机构信息

Department of Hepatobiliary and Pancreatic Surgery, No.71 Xinmin Street, First Hospital, Jilin University, Changchun, 130021, China.

Department of Thyroid Surgery, No.71 Xinmin Street, First Hospital, Jilin University, Changchun, 130021, China.

出版信息

Eur J Med Res. 2015 Apr 4;20(1):48. doi: 10.1186/s40001-015-0137-1.

Abstract

Hepatic endometriosis is one of the rarest disorders characterized by the presence of ectopic endometrium in the liver. To our knowledge, only 21 cases of hepatic endometrioma have been described in the medical literature. We report a case of a 36-year-old primiparous female with hepatic endometriosis forming a large cystic mass. The patient presented once with severe right quadrant pain as her only symptom and no history of endometriosis. Complete blood count and biochemical tests were normal. Abdominal ultrasonography and computed tomography scans suggested the presence of a 6.5 × 6.0 cm cystic mass in segment III of the liver. The mass was completely removed by local liver resection. The intraoperative frozen sections suggested a diagnosis of hepatic endometriosis. The diagnosis was confirmed through histological immunostaining without intrinsic abnormality. A preoperative diagnosis of hepatic endometriosis is made on the basis of considering the possibility in advance. Hepatic endometriosis should be considered in the differential diagnosis of a cystic liver mass despite conducting exhaustive investigations in the absence of characteristic clinical and radiological features. Histological examination is essential, and surgery remains the treatment of choice.

摘要

肝子宫内膜异位症是一种极为罕见的疾病,其特征为肝脏中存在异位子宫内膜。据我们所知,医学文献中仅描述了21例肝子宫内膜瘤病例。我们报告一例36岁初产妇,患有肝子宫内膜异位症并形成一个大的囊性肿块。该患者仅以严重的右下腹疼痛为唯一症状就诊,既往无子宫内膜异位症病史。血常规和生化检查均正常。腹部超声和计算机断层扫描显示肝脏Ⅲ段有一个6.5×6.0 cm的囊性肿块。通过局部肝切除术将肿块完全切除。术中冰冻切片提示肝子宫内膜异位症诊断。经组织学免疫染色确诊,无内在异常。肝子宫内膜异位症的术前诊断需提前考虑其可能性。尽管在缺乏特征性临床和影像学特征的情况下进行了详尽检查,但在肝囊性肿块的鉴别诊断中仍应考虑肝子宫内膜异位症。组织学检查至关重要,手术仍是首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ab/4389341/d0a1c4afe346/40001_2015_137_Fig1_HTML.jpg

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