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子宫内膜异位症:绝经前疾病?42079 例子宫内膜异位症患者的年龄模式。

Endometriosis: a premenopausal disease? Age pattern in 42,079 patients with endometriosis.

机构信息

Department of Obstetrics and Gynecology, Linz General Hospital, Krankenhausstrasse 9, 4021, Linz, Austria.

出版信息

Arch Gynecol Obstet. 2012 Sep;286(3):667-70. doi: 10.1007/s00404-012-2361-z. Epub 2012 May 5.

DOI:10.1007/s00404-012-2361-z
PMID:22562384
Abstract

PURPOSE

The objectives of this study were to examine the age distribution among women suffering from endometriosis and to establish that endometriosis is not a disease that occurs only in premenopausal women. The null hypothesis was that there are also postmenopausal women with endometriosis.

METHODS

In a retrospective epidemiological study, a descriptive analysis of data from the Federal Statistical Office in Germany for 2005 and 2006 was carried out. A total of 42,079 women in Germany were admitted for surgical treatment due to histologically confirmed endometriosis during this period. The patients' age distribution was examined and they were assigned to 5-year age groups and then to premenopausal, perimenopausal, and postmenopausal subgroups.

RESULTS

A total of 20,835 women in 2005 and 21,244 in 2006 were admitted to hospital for the treatment of endometriosis. In the premenopausal group (age 0-45 years), there were 33,814 patients (80.36 %); 23 patients (0.05 %) in this premenopausal group were younger than 15. There were 7,191 patients (17.09 %) in the perimenopausal group (45-55 years), and the postmenopausal group (55-95 years) included 1,074 patients (2.55 %).

CONCLUSIONS

The assumption that endometriosis is a disease of the premenopausal period and in women of reproductive age needs to be called into question, as well as the influence of estrogen in fully developed endometriosis. Due to the relatively high prevalence of the condition in patients aged over 40, physicians should consider endometriosis in cases of unclear pelvic pain in this age group.

摘要

目的

本研究旨在探讨子宫内膜异位症患者的年龄分布,证实子宫内膜异位症并非仅发生于绝经前女性的疾病。本研究的零假设为绝经后女性中也存在子宫内膜异位症患者。

方法

本研究采用回顾性流行病学研究方法,对德国联邦统计局 2005 年和 2006 年的数据进行描述性分析。在此期间,德国共有 42079 名女性因组织学确诊的子宫内膜异位症接受手术治疗。分析了患者的年龄分布,并将其分为 5 岁年龄组,然后分为绝经前、围绝经期和绝经后亚组。

结果

2005 年共有 20835 名女性和 2006 年 21244 名女性因子宫内膜异位症住院治疗。在绝经前组(0-45 岁),有 33814 名患者(80.36%);该绝经前组中有 23 名患者(0.05%)年龄小于 15 岁。围绝经期组(45-55 岁)有 7191 名患者(17.09%),绝经后组(55-95 岁)有 1074 名患者(2.55%)。

结论

需要对子宫内膜异位症是绝经前和生育年龄女性疾病的假设以及雌激素在完全发育的子宫内膜异位症中的作用提出质疑。由于 40 岁以上患者的发病率相对较高,对于该年龄段不明原因盆腔疼痛的患者,医生应考虑子宫内膜异位症的可能性。

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