Tripathi Dhiraj, Stanley Adrian J, Hayes Peter C, Patch David, Millson Charles, Mehrzad Homoyon, Austin Andrew, Ferguson James W, Olliff Simon P, Hudson Mark, Christie John M
Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
GI Unit, Glasgow Royal Infirmary, Glasgow, UK.
Gut. 2015 Nov;64(11):1680-704. doi: 10.1136/gutjnl-2015-309262. Epub 2015 Apr 17.
These updated guidelines on the management of variceal haemorrhage have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines which this document supersedes were written in 2000 and have undergone extensive revision by 13 members of the Guidelines Development Group (GDG). The GDG comprises elected members of the BSG liver section, representation from British Association for the Study of the Liver (BASL) and Liver QuEST, a nursing representative and a patient representative. The quality of evidence and grading of recommendations was appraised using the AGREE II tool.The nature of variceal haemorrhage in cirrhotic patients with its complex range of complications makes rigid guidelines inappropriate. These guidelines deal specifically with the management of varices in patients with cirrhosis under the following subheadings: (1) primary prophylaxis; (2) acute variceal haemorrhage; (3) secondary prophylaxis of variceal haemorrhage; and (4) gastric varices. They are not designed to deal with (1) the management of the underlying liver disease; (2) the management of variceal haemorrhage in children; or (3) variceal haemorrhage from other aetiological conditions.
这些关于静脉曲张出血管理的更新指南由英国胃肠病学会(BSG)临床服务与标准委员会(CSSC)在BSG肝脏分会的主持下委托制定。本文件取代的原始指南于2000年编写,由指南制定小组(GDG)的13名成员进行了广泛修订。GDG由BSG肝脏分会的当选成员、英国肝脏研究协会(BASL)和Liver QuEST的代表、一名护理代表和一名患者代表组成。使用AGREE II工具对证据质量和推荐分级进行了评估。肝硬化患者静脉曲张出血的性质及其复杂的并发症范围使得严格的指南并不适用。这些指南在以下小标题下专门论述了肝硬化患者静脉曲张的管理:(1)一级预防;(2)急性静脉曲张出血;(3)静脉曲张出血的二级预防;以及(4)胃静脉曲张。它们并非旨在处理(1)基础肝病的管理;(2)儿童静脉曲张出血的管理;或(3)其他病因导致的静脉曲张出血。