Huang Pei-Wen, Chang Kuo-Ming
Department of Pathology, Mackay Memorial Hospital, Hsinchu, No.690, Sec. 2, Guangfu Rd, East Dist, Hsinchu City, 30071, Taiwan.
J Med Case Rep. 2015 Mar 24;9:63. doi: 10.1186/s13256-015-0551-6.
Type AB thymoma is generally considered a benign tumor with excellent prognosis. Rare case reports of type A and AB thymomas with recurrence and metastasis have been documented, although extrathoracic metastases are extremely rare. To the best of our knowledge, this is the first reported case of type AB thymoma with solitary metastasis to the breast.
We describe an 83-year-old Taiwanese woman with a metastatic thymoma to the breast 10 years after complete resection of noninvasive and encapsulated primary tumor, and analyze the possible factors to explain the recurrence and metastasis of the stage I thymomas.
Even a clinically benign tumor such as type AB thymoma still has a possibility of metastasizing to an unusual site. When any uncommon tumor presents in any site, a suspicion of secondary neoplasm and thorough clinical history are required.
AB型胸腺瘤通常被认为是一种预后良好的良性肿瘤。虽然胸外转移极为罕见,但已有A型和AB型胸腺瘤复发和转移的罕见病例报告。据我们所知,这是首例报告的AB型胸腺瘤孤立转移至乳腺的病例。
我们描述了一名83岁的台湾女性,在无创性包膜原发性肿瘤完全切除10年后发生了胸腺瘤转移至乳腺的情况,并分析了解释I期胸腺瘤复发和转移的可能因素。
即使是像AB型胸腺瘤这样临床上的良性肿瘤,仍有可能转移至不寻常的部位。当任何部位出现任何不常见的肿瘤时,需要怀疑继发性肿瘤并详细了解临床病史。