支持血清素系统在自杀行为中作用的进一步证据：对自杀未遂者的初步研究。
Further evidence supporting the role of the serotonin system in suicidal behavior: a preliminary study of suicide attempters.
作者信息
Marazziti D, De Leo D, Conti L
机构信息
Department of Psychiatry, University of Pisa, Italy.
出版信息
Acta Psychiatr Scand. 1989 Oct;80(4):322-4. doi: 10.1111/j.1600-0447.1989.tb02987.x.
Abstract
The 3H-imipramine binding parameters (Bmax and Kd) were studied in platelets from female suicide attempters and from healthy volunteers. The Bmax was significantly lower among suicide attempters, with no modification of the Kd. These results provide support of the hypothesis that decreased serotonin function may play a role in suicidal behavior.
摘要
对女性自杀未遂者和健康志愿者血小板中的3H-丙咪嗪结合参数（最大结合容量Bmax和解离常数Kd）进行了研究。自杀未遂者的Bmax显著较低，而Kd无变化。这些结果支持了血清素功能降低可能在自杀行为中起作用这一假说。
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