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[采用频域光学相干断层扫描评估高度近视性青光眼的黄斑区脉络膜厚度]

[Foveal choroidal thickness assessment with SD-OCT in high myopic glaucoma].

作者信息

Chebil A, Maamouri R, Ben Abdallah M, Ouderni M, Chaker N, El Matri L

机构信息

Service d'ophtalmologie B, Institut Hédi-Rais d'ophtalmologie, boulevard 9-Avril, 1006 Tunis, Tunisie.

Service d'ophtalmologie B, Institut Hédi-Rais d'ophtalmologie, boulevard 9-Avril, 1006 Tunis, Tunisie.

出版信息

J Fr Ophtalmol. 2015 May;38(5):440-4. doi: 10.1016/j.jfo.2015.01.006. Epub 2015 Apr 17.

Abstract

PURPOSE

To measure macular choroidal thickness (CT) using spectral domain optical coherence tomography (OCT) in high myopic eyes with primary angle-open glaucoma (POAG), and to investigate whether the choroid is thinner in these eyes compared to high myopic eyes without glaucoma.

PATIENTS AND METHODS

We conducted a cross-sectional study of forty-eight eyes with high myopic glaucoma matched with 48 highly myopic eyes without glaucoma by age, central corneal thickness and axial length (AL). OCT scans were performed with the spectral domain OCT (Topcon 2000). The subfoveal CT was measured between the Bruch membrane and the internal aspect of the sclera.

RESULTS

In the subgroup without glaucoma, matched with the subgroup with glaucoma (P=0.57), by age, central corneal thickness (P=0.33) and AL (P=0.10), the mean subfoveal CT was 96.32 μm ± 39.56 μm. In the subgroup with glaucoma, the mean subfoveal CT was 50.44 μm ± 16.36 μm. The comparison between the two subgroups found a statistically significant difference in subfoveal CT (P<10(-4)).

CONCLUSIONS

Foveal choroidal thickness is reduced in highly myopic eyes with glaucoma. The choroidal thinning can be a useful parameter for the diagnosis and the follow-up of highly myopic patients with glaucoma.

摘要

目的

使用光谱域光学相干断层扫描(OCT)测量原发性开角型青光眼(POAG)高度近视眼中黄斑脉络膜厚度(CT),并研究与无青光眼的高度近视眼中相比,这些眼睛的脉络膜是否更薄。

患者与方法

我们进行了一项横断面研究,纳入48只高度近视性青光眼眼,并按年龄、中央角膜厚度和眼轴长度(AL)匹配48只无青光眼的高度近视眼。使用光谱域OCT(Topcon 2000)进行OCT扫描。在Bruch膜和巩膜内侧面之间测量黄斑中心凹下CT。

结果

在无青光眼亚组中,与青光眼亚组按年龄(P = 0.57)、中央角膜厚度(P = 0.33)和眼轴长度(P = 0.10)匹配后,黄斑中心凹下平均CT为96.32μm±39.56μm。在青光眼亚组中,黄斑中心凹下平均CT为50.44μm±16.36μm。两个亚组之间的比较发现黄斑中心凹下CT有统计学显著差异(P<10(-4))。

结论

青光眼高度近视眼中的黄斑脉络膜厚度降低。脉络膜变薄可能是青光眼高度近视患者诊断和随访的一个有用参数。

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