Sweeney J D, Labuzzetta J W, Michielson C E, Fitzpatrick J E
Hemophilia Center of Western New York, Buffalo.
Am J Clin Pathol. 1989 Dec;92(6):794-7. doi: 10.1093/ajcp/92.6.794.
Platelet function in platelet-rich plasma may be evaluated using an optical or electrical impedance method. Platelet function in whole blood may be studied using an impedance or particle counter method. A comparison of these techniques in whole blood has not been performed. Twenty-four healthy subjects were studied using both techniques over a range of concentrations of collagen and adenosine diphosphate (ADP). Although broad similarities exist, discordant patterns occur in individual subjects. The particle counter method is capable of detecting small aggregates and thus is more sensitive. The impedance aggregometer detects only larger aggregate formation. These techniques are complementary rather than competitive and may have considerable potential in profiling platelet function.
富血小板血浆中的血小板功能可用光学或电阻抗方法进行评估。全血中的血小板功能可用阻抗或颗粒计数法进行研究。尚未对这些全血技术进行比较。使用这两种技术对24名健康受试者在一系列胶原蛋白和二磷酸腺苷（ADP）浓度下进行了研究。虽然存在广泛的相似性，但个别受试者中出现了不一致的模式。颗粒计数法能够检测到小的聚集体，因此更敏感。阻抗聚集仪仅检测较大聚集体的形成。这些技术是互补的而非竞争性的，在分析血小板功能方面可能具有相当大的潜力。
