Lammers Jeroen, Goossens Ferry, Conrod Patricia, Engels Rutger, Wiers Reinout W, Kleinjan Marloes
Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Utrecht, The Netherlands.
Department of Psychological Medicine and Psychiatry, Section of Addiction, Kings College London, University of London, UK.
Addiction. 2015 Jul;110(7):1101-9. doi: 10.1111/add.12952.
The effectiveness of Preventure was tested on drinking behaviour of young adolescents in secondary education in the Netherlands.
A cluster randomized controlled trial was carried out, with participants assigned randomly to a two-session coping skills intervention or a control no-intervention condition.
Fifteen secondary schools throughout the Netherlands; seven schools in the intervention and eight schools in the control condition.
A total of 699 adolescents aged 13-15 years participated, 343 allocated to the intervention and 356 to the control condition, with drinking experience and elevated scores in either negative thinking, anxiety sensitivity, impulsivity or sensation-seeking.
Preventure is a selective school-based alcohol prevention programme targeting personality risk factors. The comparator was a no-intervention control.
The effects of the intervention on the primary outcome past-month binge drinking, and the secondary outcomes binge drinking frequency, alcohol use, alcohol frequency and problem drinking, were examined. The primary analyses of interest were intervention main effects at 12 months post-intervention. In addition, intervention effects on the linear development of binge drinking using a latent-growth curve approach were examined.
Binge drinking rates were not significantly different between the intervention (42.9%) and control group (49.2%) at 12 months follow-up [odds ratio (OR) = 1.05, confidence interval (CI) = 0.99, 1.11]. Intention-to-treat analyses revealed no significant intervention effects on alcohol use (53.9 versus 61.5%; OR = 0.99, CI = 0.86, 1.14) and problem drinking (37.0 versus 44.7%; OR = 1.03, CI = 0.92, 1.10) at 12 months follow-up. The post-hoc latent-growth analyses revealed significant effects on the development of binge drinking (β = -0.16, P = 0.05), and binge drinking frequency (β = -0.14, P = 0.05).
The alcohol prevention programme, Preventure, appears to have little or no effect on overall prevalence of binge drinking in adolescents in the Netherlands but may reduce the development of binge drinking over time.
在荷兰的中等教育中，对“预防计划”（Preventure）针对青少年饮酒行为的有效性进行测试。
开展了一项整群随机对照试验，参与者被随机分配到一个为期两阶段的应对技能干预组或一个无干预的对照组。
荷兰各地的15所中学；7所学校接受干预，8所学校作为对照。
共有699名13 - 15岁的青少年参与，343人被分配到干预组，356人被分配到对照组，他们有饮酒经历，且在消极思维、焦虑敏感性、冲动性或寻求刺激方面得分较高。
“预防计划”是一项针对个性风险因素的基于学校的选择性酒精预防计划。对照为无干预的对照组。
考察干预对主要结局指标（过去一个月的暴饮）以及次要结局指标（暴饮频率、酒精使用、饮酒频率和问题饮酒）的影响。主要关注的分析是干预后12个月的干预主效应。此外，采用潜在增长曲线方法考察干预对暴饮线性发展的影响。
在12个月的随访中，干预组（42.9%）和对照组（49.2%）的暴饮率无显著差异[优势比（OR）= 1.05，置信区间（CI）= 0.99, 1.11]。意向性分析显示，在12个月的随访中，干预对酒精使用（53.9%对61.5%；OR = 0.99，CI = 0.86, 1.14）和问题饮酒（37.0%对44.7%；OR = 1.03，CI = 0.92, 1.10）无显著影响。事后潜在增长分析显示，干预对暴饮的发展（β = -0.16，P = 0.05）和暴饮频率（β = -0.14，P = 0.05）有显著影响。
酒精预防计划“预防计划”似乎对荷兰青少年暴饮的总体患病率几乎没有影响，但可能会随着时间的推移减少暴饮行为的发展。
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