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经动脉化疗栓塞治疗大肝细胞癌后发生的产气荚膜梭菌感染。

Clostridium perfringens infection after transarterial chemoembolization for large hepatocellular carcinoma.

作者信息

Li Jing-Huan, Yao Rong-Rong, Shen Hu-Jia, Zhang Lan, Xie Xiao-Ying, Chen Rong-Xin, Wang Yan-Hong, Ren Zheng-Gang

机构信息

Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

出版信息

World J Gastroenterol. 2015 Apr 14;21(14):4397-401. doi: 10.3748/wjg.v21.i14.4397.

DOI:10.3748/wjg.v21.i14.4397
PMID:25892893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4394104/
Abstract

We report an unusual case of Clostridium perfringens liver abscess formation after transcatheter arterial chemoembolization (TACE) for large hepatocellular carcinoma. Severe deterioration in liver and renal function accompanied with hemocytolysis was found on the 2(nd) day after TACE. Blood culture found Clostridium perfringens and abdominal computed tomography revealed a gas-containing abscess in the liver. Following antibiotics administration and support care, the infection was controlled and the liver and renal function turned normal. The 2(nd) TACE procedure was performed 1.5 mo later and no recurrent Clostridium perfringens infection was found.

摘要

我们报告了一例罕见的病例，在对大肝细胞癌进行经动脉化疗栓塞术（TACE）后发生产气荚膜梭菌肝脓肿。TACE术后第2天发现肝肾功能严重恶化并伴有血细胞溶解。血培养发现产气荚膜梭菌，腹部计算机断层扫描显示肝脏有含气脓肿。给予抗生素治疗和支持治疗后，感染得到控制，肝肾功能恢复正常。1.5个月后进行了第二次TACE手术，未发现产气荚膜梭菌感染复发。

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