Law Siu-Tong, Lee Ming Kai
Siu-Tong Law, Ming Kai Lee, Division of Gastroenterology and Hepatology, Department of Medicine and Geriatrics, Tuen Mun Hospital, Tuen Mun, Hong Kong, China.
World J Hepatol. 2012 Aug 27;4(8):252-5. doi: 10.4254/wjh.v4.i8.252.
The pyogenic liver abscess caused by Clostridium perfringens (C. perfringens) is a rare, but rapidly fatal infection. It is usually associated with malignancy and immunosuppression. We report the case of 50-year-old lady with the secondary liver metastases from rectal cancer presented with fever and epigastric pain. The identification of Gram-positive bacilli septicaemia, the presence of gas-forming liver abscess and massive intravascular hemolysis should lead to the suspicion of C. perfringens infection. Here we review twenty cases published since 1990 and their clinical features are discussed. The importance of "an aggressive treatment policy" with multidisciplinary team approach is emphasized.
由产气荚膜梭菌引起的化脓性肝脓肿是一种罕见但迅速致命的感染。它通常与恶性肿瘤和免疫抑制有关。我们报告了一例50岁女性，患有直肠癌肝转移，出现发热和上腹部疼痛。革兰氏阳性杆菌败血症的鉴定、产气性肝脓肿的存在以及大量血管内溶血应引起对产气荚膜梭菌感染的怀疑。在此我们回顾了自1990年以来发表的20例病例，并讨论了它们的临床特征。强调了采用多学科团队方法的“积极治疗策略”的重要性。
