Galvez-Ruiz Alberto, R Nowilaty Sawsan
Neuro-ophthalmology Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia ; Unidad de Neuro-oftalmología, Hospital Ruber Internacional, Spain.
Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Saudi J Ophthalmol. 2015 Apr-Jun;29(2):160-4. doi: 10.1016/j.sjopt.2014.12.001. Epub 2014 Dec 11.
The term intermediate uveitis (IU) refers to a subgroup of uveitis in which the vitreous is the site of greatest inflammation. Patients with multiple sclerosis (MS) have a greater frequency of IU compared with the general population. The IU associated with MS is characterized by the presence of pars planitis (occasionally accompanied by anterior uveitis) and the presence of peripheral retinal vasculitis in the form of periphlebitis (venous sheathing) in 6-26% of patients. We present a patient with an unusual initial presentation of MS involving central retinal artery occlusion (CRAO) in the right eye (RE). Although retinal vascular changes are asymptomatic in the majority of MS patients, the spectrum of impairment ranges from simple peripheral retina periphlebitis to the presence of peripheral occlusive retinal vasculitis in 6.5% of patients. This atypical case may represent an extreme of the spectrum of retinal vasculitis associated with demyelinating disease.
中间葡萄膜炎（IU）这一术语指的是葡萄膜炎的一个亚组，其中玻璃体是炎症最严重的部位。与普通人群相比，多发性硬化症（MS）患者患中间葡萄膜炎的频率更高。与MS相关的中间葡萄膜炎的特征是存在睫状体平坦部炎（偶尔伴有前葡萄膜炎），并且6%-26%的患者存在以静脉周围炎（静脉鞘膜）形式出现的周边视网膜血管炎。我们报告了一名患有MS的患者，其右眼（RE）出现了不寻常的首发表现，即中央视网膜动脉阻塞（CRAO）。尽管在大多数MS患者中视网膜血管变化无症状，但损伤范围从简单的周边视网膜静脉周围炎到6.5%的患者出现周边闭塞性视网膜血管炎。这个非典型病例可能代表了与脱髓鞘疾病相关的视网膜血管炎谱系的极端情况。
