Alimi Marjan, Hofstetter Christoph P, Tsiouris Apostolos J, Elowitz Eric, Härtl Roger
Weill Cornell Brain and Spine Center, Department of Neurological Surgery, Weill Cornell Medical College, New York-Presbyterian Hospital, 525 East 68th Street, Box 99, New York, NY, 10065, USA,
Eur Spine J. 2015 Apr;24 Suppl 3:346-52. doi: 10.1007/s00586-015-3940-z. Epub 2015 Apr 18.
Asymmetric loss of disc height in adult deformity patients may lead to unilateral vertical foraminal stenosis and radiculopathy. The current study aimed to investigate whether restoration of foraminal height on the symptomatic side using extreme lateral interbody fusion (XLIF) would alleviate unilateral radiculopathy.
In a retrospective study, patients with single-level unilateral vertical foraminal stenosis and corresponding radicular pain undergoing XLIF were included. Functional data (visual analog scale (VAS) for buttock, leg and back, as well as Oswestry Disability Index (ODI)) and radiographic measurements (bilateral foraminal height, disc height, segmental coronal Cobb angle and regional lumbar lordosis) were collected preoperatively, postoperatively and at the last follow-up.
Twenty-three patients were included, among whom 61 % had degenerative scoliosis. History of previous surgery at the level of index was present in 43 % of patients. Additional instrumentation was performed in 91 %. The foraminal height on the stenotic side was significantly increased postoperatively (p < 0.001), and remained significantly increased at the last follow-up of 11 ± 3.7 months (p < 0.001). Additionally, VAS buttock and leg on the stenotic side, VAS back and ODI were significantly improved postoperatively and at the last follow-up (p ≤ 0.001 for all parameters). The foraminal height on the stenotic side showed correlation with the VAS leg on the stenotic side, both postoperatively and the last follow-up (r = -0.590; p = 0.013, and r = -0.537; p = 0.022, respectively).
Single-level XLIF is an effective procedure for treatment of symptomatic unilateral foraminal stenosis leading to radiculopathy. In deformity patients with radicular pain caused by nerve compression at a single level, when not associated with other symptoms attributable to general scoliosis, treatment with single-level XLIF can result in short- and mid-term satisfactory outcome.
成人脊柱畸形患者椎间盘高度不对称性丢失可能导致单侧椎间孔狭窄和神经根病。本研究旨在探讨采用极外侧椎间融合术(XLIF)恢复症状侧椎间孔高度是否能缓解单侧神经根病。
在一项回顾性研究中,纳入了接受XLIF治疗的单节段单侧垂直椎间孔狭窄及相应神经根性疼痛的患者。收集术前、术后及末次随访时的功能数据(臀部、腿部和背部的视觉模拟评分(VAS)以及Oswestry功能障碍指数(ODI))和影像学测量数据(双侧椎间孔高度、椎间盘高度、节段性冠状面Cobb角和腰椎前凸)。
纳入23例患者,其中61%患有退行性脊柱侧凸。43%的患者在索引节段有既往手术史。91%的患者进行了附加内固定。狭窄侧椎间孔高度术后显著增加(p < 0.001),在11±3.7个月的末次随访时仍显著增加(p < 0.001)。此外,狭窄侧臀部和腿部的VAS、背部VAS和ODI在术后及末次随访时均显著改善(所有参数p≤0.001)。狭窄侧椎间孔高度在术后及末次随访时均与狭窄侧腿部VAS呈负相关(分别为r = -0.590;p = 0.013和r = -0.537;p = 0.022)。
单节段XLIF是治疗导致神经根病的症状性单侧椎间孔狭窄的有效方法。在单节段神经受压引起神经根性疼痛的脊柱畸形患者中,当不伴有其他因脊柱侧凸引起的症状时,单节段XLIF治疗可获得短期和中期的满意疗效。