Khajavi Kaveh, Shen Alessandria, Hutchison Anthony
Georgia Spine and Neurosurgery Center, 2001 Peachtree Rd Suite 550, Atlanta, GA, USA,
Eur Spine J. 2015 Apr;24 Suppl 3:314-21. doi: 10.1007/s00586-015-3841-1. Epub 2015 Mar 24.
Conventional lumbar arthrodesis for the treatment of degenerative spondylolisthesis (DS) is associated with high complication rates and variable clinical efficacy. Modern minimally invasive (MIS) approaches may reduce the morbidity and produce greater clinical improvement compared to traditional surgical techniques. The objective of this study is to report radiographic outcomes and evaluate clinical improvements in the context of substantial clinical benefit for DS patients treated with a MIS 90° lateral, transpsoas approach for lumbar interbody fusion.
From 2005 to 2011, 60 consecutive patients were treated with MIS lateral interbody fusion for Grade I or II DS at a single institution. Mean patient age was 68 years, 75 % were female, and 30 % had undergone previous lumbar surgery. A total of 71 levels were treated, supplemental posterior fixation was used in 57 (95 %) cases, and 26 (43 %) patients underwent additional direct posterior decompression.
Average follow-up was 20.3 months. Average ORT, EBL, and LOS were 206 min, 83 cc, and 1.29 days, respectively. Complications occurred in 3 (5 %) patients. Transient approach-related thigh/groin pain was observed in 5 (8 %) cases. There were no cases of pseudoarthrosis. At 1 year, LBP improved 71 %, LP improved 68 %, ODI decreased 52 %, and SF-36 PCS and MCS improved 43 and 21 %, respectively. Substantial clinical benefit was met by 94.7 % of patients on NRS LBP, by 84.6 % on NRS LP, by 83.7 % on ODI, and by 66.7 % on SF-36 PCS. Disc height increased 71 % and segmental lordosis increased 27.8 % at treated levels. Foraminal height, width, and volume increased 19.7, 18.0, and 39.6 %, respectively. Slip improved 60.7 % with interbody fusion only and further improved to 69.2 % after the placement of supplemental instrumentation.
MIS lateral interbody fusion in the treatment of DS resulted in significant improvements in clinical and radiographic outcomes, with a low complication rate and a high proportion of patients achieving substantial clinical benefit.
传统的腰椎融合术治疗退变性腰椎滑脱(DS)并发症发生率高且临床疗效不一。与传统手术技术相比,现代微创(MIS)方法可能会降低发病率并带来更大的临床改善。本研究的目的是报告影像学结果,并在采用MIS 90°外侧经腰大肌入路进行腰椎椎间融合术治疗DS患者具有显著临床益处的背景下评估临床改善情况。
2005年至2011年,一家机构连续60例患者接受了MIS外侧椎间融合术治疗I级或II级DS。患者平均年龄68岁,75%为女性,30%曾接受过腰椎手术。共治疗71个节段,57例(95%)使用了辅助后路固定,26例(43%)患者接受了额外的直接后路减压。
平均随访20.3个月。平均手术时间、术中出血量和住院时间分别为206分钟、83毫升和1.29天。3例(5%)患者出现并发症。5例(8%)患者观察到短暂的与手术入路相关的大腿/腹股沟疼痛。无假关节形成病例。1年时,腰痛改善71%,下肢痛改善68%,ODI降低52%,SF-36身体功能和精神健康评分分别改善43%和21%。94.7%的患者在NRS腰痛评分上达到显著临床益处,84.6%在NRS下肢痛评分上达到,83.7%在ODI上达到,66.7%在SF-36身体功能评分上达到。治疗节段的椎间盘高度增加71%,节段性前凸增加27.8%。椎间孔高度、宽度和容积分别增加19.7%、18.0%和39.6%。单纯椎间融合时滑脱改善60.7%,放置辅助器械后进一步改善至69.2%。
MIS外侧椎间融合术治疗DS在临床和影像学结果方面有显著改善,并发症发生率低,且有高比例的患者获得显著临床益处。