Anders Samantha L, Peterson Carly K, James Lisa M, Engdahl Brian, Leuthold Arthur C, Georgopoulos Apostolos P
Brain Sciences Center (11B), Minneapolis Veterans Affairs Health Care System, One Veterans Drive, Minneapolis, MN, 55417, USA.
Exp Brain Res. 2015 Jul;233(7):2013-20. doi: 10.1007/s00221-015-4272-2. Epub 2015 Apr 17.
Posttraumatic growth (PTG), or positive psychological changes following exposure to traumatic events, is commonly reported among trauma survivors. In the present study, we examined neural correlates of PTG in 106 veterans with PTSD and 193 veteran controls using task-free magnetoencephalography (MEG), diagnostic interviews and measures of PTG, and traumatic event exposure. Global synchronous neural interactions (SNIs) were significantly modulated downward with increasing PTG scores in controls (p = .005), but not in veterans with PTSD (p = .601). This effect was primarily characterized by negative slopes in local neural networks, was strongest in the medial prefrontal cortex, and was much stronger and more extensive in the control than the PTSD group. The present study complements previous research highlighting the role of neural adaptation in healthy functioning.
创伤后成长（PTG），即遭受创伤事件后出现的积极心理变化，在创伤幸存者中普遍存在。在本研究中，我们使用静息态脑磁图（MEG）、诊断访谈、PTG测量以及创伤事件暴露情况，对106名患有创伤后应激障碍（PTSD）的退伍军人和193名退伍军人对照组进行了PTG的神经相关性研究。在对照组中，随着PTG得分的增加，全局同步神经交互（SNIs）显著下调（p = 0.005），但在患有PTSD的退伍军人中并非如此（p = 0.601）。这种效应主要表现为局部神经网络中的负斜率，在内侧前额叶皮质最为明显，且在对照组中比PTSD组更强、更广泛。本研究补充了先前强调神经适应在健康功能中作用的研究。
