Han Liu, Li Zhuo, Zheng Qian, Liu Jin-Ping, Li Ping-Ya
a Institute of Frontier Medical Science, Jilin University , Changchun 130021 , P.R. China.
Nat Prod Res. 2016;30(1):13-9. doi: 10.1080/14786419.2015.1030403. Epub 2015 Apr 20.
A new dammarane-type triterpenoid compound was isolated from stems and leaves of American ginseng. The structure of the new sapogenin was elucidated by the combined analysis of NMR and HR-ESI-MS as dammar-20S, 25S-epoxy-3β, 12β, 26-triol (1). Compound 1 showed cytotoxic effect on human SM7721 and human Hela cells in vitro.
从西洋参的茎和叶中分离出一种新的达玛烷型三萜化合物。通过核磁共振(NMR)和高分辨电喷雾电离质谱(HR-ESI-MS)的联合分析,确定该新皂苷元的结构为达玛-20S,25S-环氧-3β,12β,26-三醇(1)。化合物1在体外对人SM7721和人Hela细胞显示出细胞毒性作用。