Han Liu, Lin Mei-Yu, Zheng Qian, Liu Hai-Yu, Liu Hai-Yan, Dong Gang, Liu Jin-Ping, Li Ping-Ya
a Institute of Frontier Medical Science, Jilin University , Changchun 130021 , China.
Nat Prod Res. 2014;28(13):935-9. doi: 10.1080/14786419.2014.896008. Epub 2014 Apr 14.
A new minor C-3 epimer of ocotillol, named 3α-ocotillol (1), was isolated along with ocotillol (2) from the stems and leaves of American ginseng for the first time. The structure of the new sapogenin was elucidated as (20S, 24R)-dammar-20,24-epoxy-3α,6α,12β,25-tetraol by the combination analysis of NMR and mass spectrometry. The complete signal assignments of the two compounds were carried out by means of 2D NMR spectral analysis.
首次从西洋参的茎和叶中分离出一种新的奥科梯隆醇C-3差向异构体，命名为3α-奥科梯隆醇（1），同时还分离出了奥科梯隆醇（2）。通过核磁共振（NMR）和质谱的组合分析，将这种新皂苷元的结构确认为(20S, 24R)-达玛烷-20,24-环氧-3α,6α,12β,25-四醇。借助二维核磁共振光谱分析对这两种化合物进行了完整的信号归属。
