Saha N
Department of Paediatrics, Faculty of Medicine, National University of Singapore.
Am J Phys Anthropol. 1989 Nov;80(3):295-303. doi: 10.1002/ajpa.1330800303.
A total of 205 Han Chinese from two eastern provinces (155 from Fujien and 50 from Hopeh) were tested for the distribution of six blood groups--A1A2BO, MN, Rhesus (CcDEe), Lewisa, Kell (Kk) and Fya--four serum proteins--albumin and haptoglobin types; transferrin and group-specific component subtypes--haemoglobin, and twelve red cell enzyme systems--glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, lactate and malate dehydrogenases; acid phosphatase, esterate-D, glyoxalase I, adenylate kinase, glucose-phosphate isomerase, phosphoglucomutase (locus 2), and superoxide dismutase types; and phosphoglucomutase (locus 1) subtypes. The frequencies of blood groups were more or less within the reported frequencies in the Chinese. However the frequency of le was much lower in the present series. The Chinese are characterized by low p1, Ro, k, le, and a high Fya in general. P2 was lacking in the Chinese. There were some differences in the blood group frequencies in the two provinces. The frequencies of Hp alleles; Tf and Gc subtypes show characteristic mongoloid features with high Hp1, TfD, and GcIF. The frequency of TFC2 was higher in the Fujien province than that in Hopeh. At the hemoglobin locus only one Hb AD was detected, while the frequency of the beta-thalassemia trait was 0.03. No red cell G6PD deficiency or variant was detected. The distribution of red cell enzymes showed Mongoloid characteristics with low PGDC, AK2, ESD1, GLO1, and higher pa. PGM1 subtypes also had Mongoloid characteristics with lower PGM2+ and higher PGM2-. The phenotypic distribution of all the fifteen polymorphic loci was at Hardy-Weinberg equilibrium in both the Chinese populations.
对来自东部两个省份的205名汉族人（155名来自福建，50名来自河北）进行了检测，以确定六种血型——A1A2BO、MN、恒河猴血型（CcDEe）、Lewis a、Kell（Kk）和Fya——四种血清蛋白——白蛋白和触珠蛋白类型；转铁蛋白和群体特异性成分亚型——血红蛋白，以及十二种红细胞酶系统——葡萄糖-6-磷酸脱氢酶、6-磷酸葡萄糖酸脱氢酶、乳酸脱氢酶和苹果酸脱氢酶；酸性磷酸酶、酯酶-D、乙二醛酶I、腺苷酸激酶、葡萄糖磷酸异构酶、磷酸葡萄糖变位酶（位点2）和超氧化物歧化酶类型；以及磷酸葡萄糖变位酶（位点1）亚型的分布情况。血型频率或多或少在中国报道的频率范围内。然而，在本系列中，le的频率要低得多。一般来说，中国人的特征是p1、Ro、k、le频率较低，Fya频率较高。中国人中缺乏P2。两个省份的血型频率存在一些差异。触珠蛋白等位基因；转铁蛋白和Gc亚型显示出典型的蒙古人种特征，Hp1、TfD和GcIF频率较高。福建省TFC2的频率高于河北省。在血红蛋白位点仅检测到一个Hb AD，而β地中海贫血性状的频率为0.03。未检测到红细胞G6PD缺乏或变异。红细胞酶的分布显示出蒙古人种特征，PGDC、AK2、ESD1、GLO1频率较低，pa频率较高。PGM1亚型也具有蒙古人种特征，PGM2+频率较低，PGM2-频率较高。所有15个多态性位点的表型分布在两个中国群体中均处于哈迪-温伯格平衡状态。
