Weisenseel P, Reich K
Facharzt für Dermatologie und Venerologie, Allergologie, Dermatologikum Hamburg, Stephansplatz 5, 20354, Hamburg, Deutschland,
Hautarzt. 2015 Jun;66(6):408-12. doi: 10.1007/s00105-015-3628-7.
Inverse psoriasis is clinically defined by chronic inflammatory lesions in intertrigineous areas. Colonisation or infection with Candida ssp. or bacteria is common. The disease-related quality of life is significantly reduced especially regarding sexual behavior. After the exclusion of relevant differential diagnoses, therapy should be adapted to the clinical outcome and potential comorbidities. Substances which are efficacious in psoriasis vulgaris are generally efficacious in inverse psoriasis, but have to be used off-label. Controlled clinical studies are only available for topical ascomycin.
反向性银屑病在临床上表现为褶皱部位的慢性炎症性皮损。白色念珠菌或细菌的定植或感染很常见。疾病相关的生活质量显著降低,尤其是在性行为方面。排除相关鉴别诊断后,治疗应根据临床结果和潜在合并症进行调整。对寻常型银屑病有效的药物通常对反向性银屑病也有效,但必须超适应证使用。目前仅有关于外用子囊霉素的对照临床研究。