Stowkowy Jacqueline, Liu Lu, Cadenhead Kristin S, Cannon Tyrone D, Cornblatt Barbara A, McGlashan Thomas H, Perkins Diana O, Seidman Larry J, Tsuang Ming T, Walker Elaine F, Woods Scott W, Bearden Carrie E, Mathalon Daniel H, Heinssen Robert, Addington Jean
University of Calgary,Canada.
UCSD,La Jolla,USA.
Behav Cogn Psychother. 2016 Mar;44(2):203-13. doi: 10.1017/S1352465815000144. Epub 2015 Apr 21.
Schema Theory proposes that the development of maladaptive schemas are based on a combination of memories, emotions and cognitions regarding oneself and one's relationship to others. A cognitive model of psychosis suggests that schemas are crucial to the development and persistence of psychosis. Little is known about the impact that schemas may have on those considered to be at clinical high risk (CHR) of developing psychosis.
To investigate schemas over time in a large sample of CHR individuals and healthy controls.
Sample included 765 CHR participants and 280 healthy controls. Schemas were assessed at baseline, 6 and 12 months using the Brief Core Schema Scale (BCSS). Baseline schemas were compared to 2-year clinical outcome.
CHR participants evidenced stable and more maladaptive schemas over time compared to controls. Schemas at initial contact did not vary amongst the different clinical outcome groups at 2 years although all CHR outcome groups evidenced significantly worse schemas than healthy controls. Although there were no differences on baseline schemas between those who later transitioned to psychosis compared to those who did not, those who transitioned to psychosis had more maladaptive negative self-schemas at the time of transition. Associations between negative schemas were positively correlated with earlier abuse and bullying.
These findings demonstrate a need for interventions that aim to improve maladaptive schemas among the CHR population. Therapies targeting self-esteem, as well as schema therapy may be important work for future studies.
图式理论提出,适应不良图式的形成基于关于自身以及自身与他人关系的记忆、情感和认知的综合作用。一种精神病认知模型表明,图式对于精神病的发展和持续存在至关重要。对于图式可能对那些被认为处于精神病临床高危状态(CHR)的人群产生的影响,人们了解甚少。
在大量CHR个体和健康对照样本中,对图式进行长期研究。
样本包括765名CHR参与者和280名健康对照。使用简短核心图式量表(BCSS)在基线、6个月和12个月时评估图式。将基线图式与2年临床结局进行比较。
与对照组相比,CHR参与者随着时间推移表现出稳定且更适应不良的图式。尽管所有CHR结局组的图式均明显比健康对照差,但在2年时,不同临床结局组在初次接触时的图式并无差异。虽然后来发展为精神病的人与未发展为精神病的人在基线图式上没有差异,但发展为精神病的人在转变时具有更多适应不良的消极自我图式。消极图式之间的关联与早期的虐待和欺凌呈正相关。
这些发现表明需要开展旨在改善CHR人群中适应不良图式的干预措施。针对自尊的治疗以及图式治疗可能是未来研究的重要工作。