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连续注射贝伐单抗联合激光光凝治疗视网膜动脉大动脉瘤相关黄斑水肿

Serial bevacizumab injections and laser photocoagulation for macular edema associated with a retinal artery macroaneurysm.

作者信息

Leung Ella H, Reddy Ashvini K, Vedula Anil S, Flynn Harry W

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.

Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA.

出版信息

Clin Ophthalmol. 2015 Apr 4;9:601-9. doi: 10.2147/OPTH.S80504. eCollection 2015.

Abstract

An 84-year-old female with a history of hypertension and dyslipidemia was referred for a retinal artery macroaneurysm with exudation that had extended into the macula. She underwent a total of six injections of bevacizumab, with some improvement in visual acuity and retinal thickness. Due to persistent macular edema, focal laser photocoagulation was performed around the macroaneurysm. The vision remained at 20/30 during 20 months of follow up. Although anti-vascular endothelial growth factor therapy may improve vision and decrease retinal thickness in retinal artery macroaneurysm, recalcitrant cases may be treated with laser photocoagulation to seal the leaking vessel.

摘要

一位84岁女性,有高血压和血脂异常病史,因视网膜动脉大动脉瘤伴渗出并累及黄斑而前来就诊。她总共接受了6次贝伐单抗注射,视力和视网膜厚度有一定改善。由于黄斑水肿持续存在,在大动脉瘤周围进行了局部激光光凝治疗。在20个月的随访期间,视力维持在20/30。尽管抗血管内皮生长因子治疗可能改善视网膜动脉大动脉瘤患者的视力并降低视网膜厚度,但对于顽固病例,可采用激光光凝治疗来封闭渗漏血管。

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