Sahebi Leyla, Ansarin Khalil, Maryam Seyyedi, Monfaredan Amir, Sabbgh Jadid Hamed
Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Science, Daneshgah Street, Postal code 51665118, Tabriz, Iran.
Department of Hematology, Tabriz branch, Islamic Azad University of Tabriz, Daneshgah Street, Postal code 51665118, Tabriz, Iran.
Malays J Med Sci. 2014 Nov-Dec;21(6):27-35.
Identifying the factors associated with the recurrence of Mycobacterium tuberculosis (MTB) can help in tuberculosis disease prevention and reducing the burden on the health care system. This study was designed to identify the factors associated with recurrence in MTB patients in five border provinces of Iran.
In a cross-sectional study (2010 to 2012), clinical, economic, and social factors associated with the recurrence of tuberculosis were evaluated. The data were collected by a questionnaire and survey of medical records. Simple and multiple logistic regression analyses were performed using SPSS V.18.
A total of 300 patients with an average age of 51.9 years (SD 24.2) were randomly selected. Overall, 7.2% of the patients were diagnosed with a recurrence of tuberculosis. Sixty-four percent (n = 151) of the patients were in a low-income class. The migration from a village to a city (OR = 8.4) and weight loss (OR = 1.5) were significantly associated with an increased chance of recurrence.
In this study, the selected provinces of Iran had moderate rates of tuberculosis recurrence in comparison to global reports. Further studies on the relationship of both weight loss and the immigration from a village to a city with tuberculosis recurrence are necessary.
确定与结核分枝杆菌（MTB）复发相关的因素有助于预防结核病并减轻医疗保健系统的负担。本研究旨在确定伊朗五个边境省份MTB患者复发的相关因素。
在一项横断面研究（2010年至2012年）中，评估了与结核病复发相关的临床、经济和社会因素。通过问卷调查和病历调查收集数据。使用SPSS V.18进行单因素和多因素逻辑回归分析。
共随机选取300例平均年龄为51.9岁（标准差24.2）的患者。总体而言，7.2%的患者被诊断为结核病复发。64%（n = 151）的患者属于低收入阶层。从农村迁移到城市（比值比 = 8.4）和体重减轻（比值比 = 1.5）与复发几率增加显著相关。
在本研究中，与全球报告相比，伊朗选定省份的结核病复发率中等。有必要进一步研究体重减轻以及从农村迁移到城市与结核病复发之间的关系。
