Tipton Charles M
Department of Physiology, University of Arizona, Ina Gittings Building, Room 205 A, AZ 85721 Tucson, USA.
Extrem Physiol Med. 2015 Apr 17;4:6. doi: 10.1186/s13728-015-0024-y. eCollection 2015.
This invited autobiographical article pertains to 52 years as an exercise physiologist of which 16 years were devoted to being an active emeriti. Although the career pathway was circuitous in nature, once resolved, it included preparation of future exercise physiologists; reducing the health hazards associated with the "making of weight" by scholastic wrestlers; using animals (rats and dogs) as the model system with a myriad of experimental procedure for obtaining insights and understandings of various exercise training mechanism in one-G environments, and in simulated μG environments. From the results, we have concluded that (a) inactivity, as represented by immobilization, is the most undesirable physiological state an animal should experience and (b) movement, as represented by training, will have an intrinsic adaptive influence on select biological tissues that, in some situations, can be independent of autonomic and hormonal influences.
这篇受邀撰写的自传体文章讲述了我作为一名运动生理学家的52年职业生涯，其中16年是作为活跃的荣誉退休人员度过的。尽管职业道路曲折，但一旦确定下来，它包括培养未来的运动生理学家；减少学校摔跤运动员“控制体重”带来的健康危害；使用动物（大鼠和狗）作为模型系统，通过无数实验程序来深入了解和认识1G环境以及模拟微重力环境中的各种运动训练机制。从结果来看，我们得出结论：(a) 以固定不动为代表的不活动状态是动物应经历的最不利生理状态；(b) 以训练为代表的运动对某些生物组织具有内在的适应性影响，在某些情况下，这种影响可以独立于自主神经和激素的影响。
