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Fixing a hole: CCN2 closes chronic wounds.

作者信息

Leask Andrew

机构信息

Department of Dentistry, Department of Physiology and Pharmacology, University of Western Ontario, London, ON, Canada, N6A 5C1.

出版信息

J Cell Commun Signal. 2015 Sep;9(3):281-2. doi: 10.1007/s12079-015-0292-8. Epub 2015 Apr 22.

DOI:10.1007/s12079-015-0292-8
PMID:25899386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4580677/
Abstract
摘要

相似文献

1
Fixing a hole: CCN2 closes chronic wounds.填补漏洞:CCN2促进慢性伤口愈合。
J Cell Commun Signal. 2015 Sep;9(3):281-2. doi: 10.1007/s12079-015-0292-8. Epub 2015 Apr 22.
2
Inflammatory microenvironment and tumor necrosis factor alpha as modulators of periostin and CCN2 expression in human non-healing skin wounds and dermal fibroblasts.炎症微环境和肿瘤坏死因子-α作为人非愈合性皮肤创面和真皮成纤维细胞中骨膜蛋白和 CCN2 表达的调节剂。
Matrix Biol. 2015 Apr;43:71-84. doi: 10.1016/j.matbio.2015.03.003. Epub 2015 Mar 14.
3
CCN2 is transiently expressed by keratinocytes during re-epithelialization and regulates keratinocyte migration in vitro by the ras-MEK-ERK signaling pathway.CCN2 在角质形成细胞再上皮化过程中短暂表达,并通过 ras-MEK-ERK 信号通路调节角质形成细胞的迁移。
J Surg Res. 2013 Dec;185(2):e109-19. doi: 10.1016/j.jss.2013.05.065. Epub 2013 Jun 10.
4
Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts.Akt 抑制通过 CCN2 依赖性途径在上皮成纤维细胞中上调 MMP1。
Exp Dermatol. 2010 Apr;19(4):347-54. doi: 10.1111/j.1600-0625.2010.01065.x. Epub 2010 Feb 25.
5
CCN2 induces cellular senescence in fibroblasts.CCN2可诱导成纤维细胞发生细胞衰老。
J Cell Commun Signal. 2017 Mar;11(1):15-23. doi: 10.1007/s12079-016-0359-1. Epub 2016 Oct 18.
6
Correlation of Connective Tissue Growth Factor (CTGF/CCN2) with Hepatic Fibrosis in Chronic Hepatitis B.慢性乙型肝炎中结缔组织生长因子(CTGF/CCN2)与肝纤维化的相关性
Mymensingh Med J. 2015 Jul;24(3):558-63.
7
Periostin and CCN2 Scaffolds Promote the Wound Healing Response in the Skin of Diabetic Mice.骨膜蛋白和 CCN2 支架促进糖尿病小鼠皮肤的伤口愈合反应。
Tissue Eng Part A. 2019 Sep;25(17-18):1326-1339. doi: 10.1089/ten.TEA.2018.0268. Epub 2019 Feb 27.
8
Atrial expression of the CCN1 and CCN2 proteins in chronic heart failure.慢性心力衰竭时CCN1和CCN2蛋白的心房表达。
Folia Histochem Cytobiol. 2012 Apr 24;50(1):99-103. doi: 10.2478/18703.
9
Cellular communication network factor 2 (CCN2) promotes the progression of acute kidney injury to chronic kidney disease.细胞通讯网络因子 2(CCN2)促进急性肾损伤向慢性肾脏病的进展。
Biochem Biophys Res Commun. 2019 Sep 10;517(1):96-102. doi: 10.1016/j.bbrc.2019.07.024. Epub 2019 Jul 15.
10
A perspective on anti-CCN2 therapy for chronic kidney disease.慢性肾脏病抗CCN2治疗的前景
Nephrol Dial Transplant. 2014 Feb;29 Suppl 1:i30-i37. doi: 10.1093/ndt/gft430.

本文引用的文献

1
The role of CTGF in diabetic retinopathy.结缔组织生长因子在糖尿病视网膜病变中的作用。
Exp Eye Res. 2015 Apr;133:37-48. doi: 10.1016/j.exer.2014.10.016.
2
Topically applied connective tissue growth factor/CCN2 improves diabetic preclinical cutaneous wound healing: potential role for CTGF in human diabetic foot ulcer healing.局部应用结缔组织生长因子/CCN2可改善糖尿病临床前皮肤伤口愈合:CTGF在人类糖尿病足溃疡愈合中的潜在作用。
J Diabetes Res. 2015;2015:236238. doi: 10.1155/2015/236238. Epub 2015 Feb 18.
3
CCN2 is required for recruitment of Sox2-expressing cells during cutaneous tissue repair.在皮肤组织修复过程中,招募表达Sox2的细胞需要CCN2。
J Cell Commun Signal. 2015 Dec;9(4):341-6. doi: 10.1007/s12079-014-0245-7. Epub 2014 Oct 18.
4
CCN2 expression by fibroblasts is not required for cutaneous tissue repair.成纤维细胞中 CCN2 的表达对于皮肤组织修复并非必需。
Wound Repair Regen. 2014 Jan-Feb;22(1):119-24. doi: 10.1111/wrr.12131.
5
Human skin wounds: a major and snowballing threat to public health and the economy.人类皮肤创伤:对公共健康和经济的重大且不断加剧的威胁。
Wound Repair Regen. 2009 Nov-Dec;17(6):763-71. doi: 10.1111/j.1524-475X.2009.00543.x.
6
Connective tissue growth factor: context-dependent functions and mechanisms of regulation.结缔组织生长因子:依赖于环境的功能及调控机制
Biofactors. 2009 Mar-Apr;35(2):200-8. doi: 10.1002/biof.30.
7
Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?结缔组织生长因子(CCN2),糖尿病肾病的致病因子。它是做什么的?它是如何发挥作用的?
J Cell Commun Signal. 2009 Jun;3(2):95-104. doi: 10.1007/s12079-009-0038-6. Epub 2009 Feb 14.
8
The epidemiology of lower extremity amputations in diabetic individuals.糖尿病患者下肢截肢的流行病学
Diabetes Care. 1983 Jan-Feb;6(1):87-91. doi: 10.2337/diacare.6.1.87.