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过敏性儿童特异性IgE和IgG4抗体的临床研究。II型多因素分析检测。(客观变量:食物过敏原特异性IgE抗体和IgG4抗体)

[Clinical research of specific IgE and IgG4 antibody in allergic children. Examination by multiple factor analysis-type II. (objective variables: specific IgE antibodies and IgG4 antibodies to food allergen)].

作者信息

Nagata K

出版信息

Arerugi. 1989 May;38(5):391-406.

PMID:2589975
Abstract

We examined the influence power of 16 explanation variables to specific IgE antibody and IgG4 antibody to egg white cow's milk, and soybean in 150 asthmatic children by Multiple Factor Analysis-Type II 16 examination variables; 1) sex, 2) age, 3) onset age, 4) IgE RIST, 5) eosinophile count, 6) IgE RAST score to house dust, 7) IgE RAST score to Dermatophagoids farinae, 8) atopic dermatitis, 9) allergic rhinitis, 10) family history of allergy, 11) positive counts of food allergen: IgG4, 12) specific IgG4 antibody to cow's milk, 13) specific IgG4 antibody to soybean, 14) exercise induced asthma, 15) severity of asthma. The following results were obtained. 1) To introduce range relative ratio, we were able to use all 16 explanation variables on the occation of calculating by Multiple Factor Analysis-Type II. 2) 4 explanation variables (specific IgG4 antibody to soybean, IgE RIST, IgE RAST score to Dermatophgoides farinae, age) had the stronger influence power to 8 objective variables than the other explanation variables. 3) Only 2 explanation variables (specific IgE antibody to soybean, family history of allergy) had the stronger influence power to 8 objective variables than the other explanation variables.

摘要

我们通过多因素分析II型,对150名哮喘儿童中16个解释变量对蛋清、牛奶和大豆特异性IgE抗体及IgG4抗体的影响能力进行了研究。16个检测变量如下:1)性别,2)年龄,3)发病年龄,4)IgE RIST,5)嗜酸性粒细胞计数,6)对屋尘的IgE RAST评分,7)对粉尘螨的IgE RAST评分,8)特应性皮炎,9)变应性鼻炎,10)过敏家族史,11)食物过敏原IgG4阳性计数,12)牛奶特异性IgG4抗体,13)大豆特异性IgG4抗体,14)运动诱发性哮喘,15)哮喘严重程度。得到以下结果。1)为引入范围相对比,在通过多因素分析II型进行计算时,我们能够使用所有16个解释变量。2)4个解释变量(大豆特异性IgG4抗体、IgE RIST、对粉尘螨的IgE RAST评分、年龄)对8个目标变量的影响能力比其他解释变量更强。3)只有2个解释变量(大豆特异性IgE抗体、过敏家族史)对8个目标变量的影响能力比其他解释变量更强。

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