Koya N, Suzuki S, Hara M, Nagata K, Tateno A, Moroi T, Iikura Y
Arerugi. 1989 Jun;38(6):466-77.
We analysed the correlation specific IgE antibodies to specific IgG4 antibodies to food allergens in 150 asthmatic children by Multiple Factor Analysis-Type II and examined the role of both antibodies. The following results were obtained. 1) Of soybean, there was the stronger influence power between specific IgE and IgG4 antibody than the other 2 food allergens. 2) IgE antibody to soybean had the strong influence power to IgG4 antibodies to egg white and cow's milk and IgG4 antibody to soybean had same influence power to IgE antibodies to egg white and cow's milk. So, the specific IgE and IgG4 antibodies to soybean may be play the role of "the bride" between specific IgE antibody group and specific IgG4 antibody group of food allergens.
我们通过多因素分析II型对150名哮喘儿童中针对食物过敏原的特异性IgE抗体与特异性IgG4抗体之间的相关性进行了分析，并研究了这两种抗体的作用。得到了以下结果。1）在大豆方面，特异性IgE和IgG4抗体之间的影响力比其他两种食物过敏原更强。2）大豆特异性IgE抗体对蛋清和牛奶的IgG4抗体有很强的影响力，而大豆特异性IgG4抗体对蛋清和牛奶的IgE抗体有相同的影响力。因此，大豆特异性IgE和IgG4抗体可能在食物过敏原的特异性IgE抗体组和特异性IgG4抗体组之间起到“桥梁”作用。
