Iwamuro Masaya, Okada Hiroyuki, Matsueda Kazuhiro, Inaba Tomoki, Kusumoto Chiaki, Imagawa Atsushi, Yamamoto Kazuhide
Masaya Iwamuro, Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan.
World J Gastrointest Endosc. 2015 Apr 16;7(4):336-45. doi: 10.4253/wjge.v7.i4.336.
The formation of a bezoar is a relatively infrequent disorder that affects the gastrointestinal system. Bezoars are mainly classified into four types depending on the material constituting the indigestible mass of the bezoar: phytobezoars, trichobezoars, pharmacobezoars, and lactobezoars. Gastric bezoars often cause ulcerative lesions in the stomach and subsequent bleeding, whereas small intestinal bezoars present with small bowel obstruction and ileus. A number of articles have emphasized the usefulness of Coca-Cola(®) administration for the dissolution of phytobezoars. However, persimmon phytobezoars may be resistant to such dissolution treatment because of their harder consistency compared to other types of phytobezoars. Better understanding of the etiology and epidemiology of each type of bezoar will facilitate prompt diagnosis and management. Here we provide an overview of the prevalence, classification, predisposing factors, and manifestations of bezoars. Diagnosis and management strategies are also discussed, reviewing mainly our own case series. Recent progress in basic research regarding persimmon phytobezoars is also briefly reviewed.
胃石形成是一种相对罕见的影响胃肠系统的病症。胃石主要根据构成胃石难消化团块的物质分为四种类型：植物性胃石、毛发胃石、药物性胃石和乳酸性胃石。胃内胃石常导致胃部溃疡性病变及随后的出血，而小肠胃石则表现为小肠梗阻和肠梗阻。许多文章强调了饮用可口可乐（®）对溶解植物性胃石的有效性。然而，与其他类型的植物性胃石相比，柿子植物性胃石因其质地较硬，可能对这种溶解治疗有抗性。更好地了解每种类型胃石的病因和流行病学将有助于及时诊断和处理。在此，我们概述胃石的患病率、分类、易感因素和表现。还讨论了诊断和处理策略，主要回顾了我们自己的病例系列。也简要回顾了关于柿子植物性胃石基础研究的最新进展。
