Chandrashekar Vani
a Department of Hematology , Apollo Hospitals , Chennai , Tamil Nadu , India.
Platelets. 2015;26(7):699-701. doi: 10.3109/09537104.2015.1026318. Epub 2015 Apr 22.
Light transmission aggregometry lacks in standardisation and normal reference values are not widely available. The aims of our study were to establish reference ranges for aggregation, slope and lag phase in healthy controls with platelet counts between 150 and 450 × 10(9)/l in platelet-rich plasma (PRP) as well as evaluate the influence of platelet count. Ninety-nine subjects were evaluated with four agonists and divided into two groups based on platelet count and the groups were compared by Student's t-test. There was no difference between the means of the two groups for amplitude and slope barring the lag phase for collagen. Platelet counts between 150 and 450 × 10(9)/l have no effects on light transmission aggregometry and hence adjustment of platelet count is not necessary.
光透射聚集测定法缺乏标准化，且正常参考值尚未广泛可得。我们研究的目的是为富含血小板血浆（PRP）中血小板计数在150至450×10⁹/L之间的健康对照者建立聚集、斜率和延迟期的参考范围，并评估血小板计数的影响。对99名受试者使用四种激动剂进行评估，并根据血小板计数分为两组，两组通过学生t检验进行比较。除了胶原的延迟期外，两组在振幅和斜率的均值上没有差异。血小板计数在150至450×10⁹/L之间对光透射聚集测定法没有影响，因此无需调整血小板计数。
