Dimakakos Evangelos P, Katsenis K, Kalemikerakis J, Arkadopoulos N, Mylonas S, Arapoglou V, Tsiganis T, Kotis T
Vascular Unit, Aretaieion University Hospital of Athens, Maroussi, Greece; Email:
Wounds. 2009 Jan;21(1):4-8.
The aim of this work was to study the safety and effectiveness of silver foam dressing (Contreet® Ag, Coloplast, Humlebaek, Denmark) in promoting the healing of infected venous ulcers over 9 weeks of treatment. Forty-two patients with infected venous ulcers were included and randomized into two groups. Group A had 21 patients (12 women and 9 men, mean age 61.2 years) who were treated with the silver foam for 9 weeks. Group B also had 21 patients (14 women and 7 men, mean age 58.7 years) who were treated with a nonadhesive foam (Biatain®, Coloplast, Humlebaek, Denmark) for 9 weeks. In both groups, ulcer size and depth, intensity of pain, wound exudation, bacterial load, side effects of both materials, and ulcer healing were documented and compared. There was no significant difference at the initial assessment in both groups regarding ulcer size, ulcer depth, grade of exudation, pain intensity, or bacterial load. However, group A ulcers had a significantly greater healing (P = 0.02) compared to group B. Pain intensity was significantly less in group A patients at several time points. After 9 weeks of treatment, the silver foam dressing was found to be a safe material that promotes rapid healing of venous ulcers and relieves pain. .
这项工作的目的是研究银泡沫敷料（Contreet® Ag，康乐保公司，丹麦胡姆勒拜克）在9周治疗期内促进感染性静脉溃疡愈合的安全性和有效性。纳入42例感染性静脉溃疡患者并随机分为两组。A组有21例患者（12名女性和9名男性，平均年龄61.2岁），接受银泡沫敷料治疗9周。B组也有21例患者（14名女性和7名男性，平均年龄58.7岁），接受非粘性泡沫敷料（Biatain®，康乐保公司，丹麦胡姆勒拜克）治疗9周。记录并比较两组的溃疡大小和深度、疼痛强度、伤口渗出情况、细菌载量、两种材料的副作用以及溃疡愈合情况。两组在初始评估时，溃疡大小、溃疡深度、渗出等级、疼痛强度或细菌载量方面均无显著差异。然而，与B组相比，A组溃疡愈合程度明显更高（P = 0.02）。在几个时间点，A组患者的疼痛强度明显更低。经过9周治疗后，发现银泡沫敷料是一种安全的材料，可促进静脉溃疡快速愈合并缓解疼痛。
