Tkach S M, Balabantseva H P, Levchenko A R
Lik Sprava. 2014 May-Jun(5-6):38-47.
In the article the incidence, pathogenesis, clinical featuries, diagnostic, prevention and treatment of NSAIDs-induced injuries of small intestine are presented. The different strategies of management of NSAID-induced enteropathy, such as use of PPI, COX-2-inhibitors, prostaglandins, antibiotics and probiotics, new combination of NSAIDs with phosphatidylcholine, NO or H2S, food supplements and other drugs are discussed.
本文介绍了非甾体抗炎药(NSAIDs)所致小肠损伤的发病率、发病机制、临床特征、诊断、预防及治疗。讨论了NSAIDs所致小肠病的不同治疗策略,如使用质子泵抑制剂(PPI)、COX-2抑制剂、前列腺素、抗生素和益生菌,NSAIDs与磷脂酰胆碱、一氧化氮或硫化氢的新联合用药、食品补充剂及其他药物。