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非创伤性脑出血的诊断评估

Diagnostic evaluation for nontraumatic intracerebral hemorrhage.

作者信息

Domingues Renan, Rossi Costanza, Cordonnier Charlotte

机构信息

Department of Neurology, University of Lille, UDSL, CHU Lille, Inserm U 1171, Lille 59000, France; CAPES Foundation, Ministry of Education, Quadra 2, Bloco L, Lote 06, Edifício Capes - CEP: 70.040-020 - Brasilia-DF, Brazil.

Department of Neurology, University of Lille, UDSL, CHU Lille, Inserm U 1171, Lille 59000, France.

出版信息

Neurol Clin. 2015 May;33(2):315-28. doi: 10.1016/j.ncl.2014.12.001.

Abstract

Intracerebral hemorrhage (ICH) is a devastating condition with multiple possible underlying causes. Early diagnosis of ICH associated with a precise diagnostic work-up is mandatory. Clinical signs may give clues to diagnosis but are not reliable enough and imaging remains the cornerstone of management. Noncontrast computed tomography and magnetic resonance imaging (MRI) are highly sensitive for ICH identification. Additionally, MRI may disclose brain parenchymal biomarkers that can contribute to the etiologic diagnosis. Vessel examination should be carried out whenever there is a clinical suspicion of underlying structural lesions, such as vascular malformations or tumors. To date, conventional angiography remains the gold standard to detect intracranial vascular malformations in patients with ICH.

摘要

脑出血(ICH)是一种具有多种潜在病因的严重疾病。对与精确诊断检查相关的脑出血进行早期诊断至关重要。临床体征可能为诊断提供线索,但不够可靠,影像学检查仍然是治疗的基石。非增强计算机断层扫描和磁共振成像(MRI)对脑出血的识别高度敏感。此外,MRI可能会揭示有助于病因诊断的脑实质生物标志物。每当临床怀疑存在潜在结构性病变,如血管畸形或肿瘤时,都应进行血管检查。迄今为止,传统血管造影仍是检测脑出血患者颅内血管畸形的金标准。

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