Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Molndal, Sweden.
Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Molndal, Sweden.
J Card Fail. 2015 Sep;21(9):702-7. doi: 10.1016/j.cardfail.2015.04.006. Epub 2015 Apr 20.
The objective of the present study was to investigate whether mild cognitive deficits are present in patients with heart failure (HF) despite absence of any known cognitive disorder.
A well defined group of patients (n = 40) with heart failure completed a cognitive screening check list, a depression screening questionnaire, and a battery consisting of neuropsychological tests assessing 5 different cognitive domains: speed/attention, episodic memory, visuospatial functions, language, and executive functions. The neuropsychological results were compared with those from a group of healthy control subjects (n = 41). The patients with HF displayed cognitive impairment compared with the control group within the domains speed and attention, episodic memory, visuospatial functions, and language. Among them, 34 HF patients (85%) could be classified with mild cognitive impairment (MCI), the majority as nonamnestic MCI, ie, with no memory impairment.
Considering the high occurrence of mild cognitive deficits among HF patients without known cognitive disorders, closer attention should be paid to their self-care and compliance. Inadequate self-care and compliance could lead to more frequent hospitalizations. Furthermore, the HF patients may be at increased risk of dementia.
本研究旨在调查即使没有任何已知认知障碍，心力衰竭（HF）患者是否存在轻度认知缺陷。
一组明确的心力衰竭患者（n=40）完成了认知筛查清单、抑郁筛查问卷以及一系列神经心理学测试，这些测试评估了 5 个不同的认知领域：速度/注意力、情景记忆、视空间功能、语言和执行功能。将神经心理学结果与一组健康对照组（n=41）进行比较。与对照组相比，HF 患者在速度和注意力、情景记忆、视空间功能和语言等领域表现出认知障碍。其中，34 名 HF 患者（85%）可被归类为轻度认知障碍（MCI），大多数为非遗忘性 MCI，即无记忆障碍。
考虑到无已知认知障碍的 HF 患者中轻度认知缺陷的高发生率，应更加关注他们的自我护理和依从性。自我护理和依从性不足可能导致更频繁的住院治疗。此外，HF 患者患痴呆的风险可能增加。
