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从人类病例中分离出的东部马脑炎病毒和委内瑞拉马脑炎病毒株的完整编码序列。

Complete coding sequences of eastern equine encephalitis virus and venezuelan equine encephalitis virus strains isolated from human cases.

作者信息

Yu Guo-Yun, Wiley Michael R, Kugelman Jeffrey R, Ladner Jason T, Beitzel Brett F, Eccleston Lori T, Morazzani Elaine M, Glass Pamela J, Palacios Gustavo F

机构信息

Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.

Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.

出版信息

Genome Announc. 2015 Apr 23;3(2):e00243-15. doi: 10.1128/genomeA.00243-15.

Abstract

We obtained the complete coding genome of an eastern equine encephalitis virus (EEEV) strain, EEEV V105-00210, and the complete genome of a Venezuelan equine encephalitis virus (VEEV) strain, VEEV INH-9813. They were obtained from human cases and are proposed as reference challenge strains for vaccine and therapeutic development in animal models.

摘要

我们获得了一株东部马脑炎病毒(EEEV)V105 - 00210毒株的完整编码基因组,以及一株委内瑞拉马脑炎病毒(VEEV)INH - 9813毒株的完整基因组。它们源自人类病例,被提议作为动物模型中疫苗和治疗药物研发的参考攻击毒株。

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