Department of Environmental Health Engineering, School of public Health, Iran University of Medical Sciences, Tehran, Iran.
Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
J Environ Health Sci Eng. 2015 Apr 21;13:35. doi: 10.1186/s40201-015-0194-y. eCollection 2015.
Metronidazole (MNZ) is a brand of nitroimidazole antibiotic, which is generally used in clinical applications and extensively used for the treatment of infectious diseases caused by anaerobic bacteria and protozoans. The aim of this investigation was to degrade MNZ with illuminated TiO2 nanoparticles at different catalyst dosage, contact time, pH, initial MNZ concentration and lamp intensity. Maximum removal of MNZ was observed at near neutral pH. Removal efficiency was decreased by increasing dosage and initial MNZ concentration. The reaction rate constant (k obs ) was decreased from 0.0513 to 0.0072 min(-1) and the value of electrical energy per order (EEo) was increased from 93.57 to 666.67 (kWh/m(3)) with increasing initial MNZ concentration from 40 to 120 mg/L, respectively. The biodegradability estimated from the BOD5/COD ratio was increased from 0 to 0.098. The photocatalyst demonstrated proper photocatalytic activity even after five successive cycles. Finally, UV/TiO2 is identified as a promising technique for the removal of antibiotic with high efficiency in a relatively short reaction time.
甲硝唑（MNZ）是一种硝基咪唑类抗生素品牌，通常用于临床应用，广泛用于治疗由厌氧菌和原生动物引起的传染病。本研究旨在用光催化 TiO2 纳米粒子在不同催化剂用量、接触时间、pH 值、初始 MNZ 浓度和灯强度下对 MNZ 进行降解。在近中性 pH 值下观察到 MNZ 的最大去除率。去除效率随着剂量和初始 MNZ 浓度的增加而降低。反应速率常数（k obs ）从 0.0513 降至 0.0072 min(-1)，电能每阶（EEo）的值从 93.57 增至 666.67（kWh/m(3)），初始 MNZ 浓度从 40 增至 120 mg/L，分别。从 BOD5/COD 比估算的生物降解性从 0 增加到 0.098。即使经过五次连续循环，光催化剂仍表现出适当的光催化活性。最后，UV/TiO2 被确定为一种有前途的技术，可在相对较短的反应时间内高效去除抗生素。
