Somersalo Axel, Paloneva Juha, Kautiainen Hannu, Lönnroos Eija, Heinänen Mikko, Kiviranta Ilkka
a 1 Orthopaedics and Traumatology , University of Helsinki, Helsinki.
b 2 Department of Orthopaedics and Traumatology , Central Finland Hospital, Jyväskylä
Acta Orthop. 2015;86(5):533-57. doi: 10.3109/17453674.2015.1043833.
Increased mortality after hip fracture is well documented. The mortality after hospitalization for upper extremity fracture is unknown, even though these are common injuries. Here we determined mortality after hospitalization for upper extremity fracture in patients aged ≥16 years.
We collected data about the diagnosis code (ICD10), procedure code (NOMESCO), and 7 additional characteristics of 5,985 patients admitted to the trauma ward of Central Finland Hospital between 2002 and 2008. During the study, 929 women and 753 men sustained an upper extremity fracture. The patients were followed up until the end of 2012. Mortality rates were calculated using data on the population at risk.
By the end of follow-up (mean duration 6 years), 179 women (19%) and 105 men (14%) had died. The standardized mortality ratio (SMR) for all patients was 1.5 (95% CI: 1.4-1.7). The SMR was higher for men (2.1, CI: 1.7-2.5) than for women (1.3, CI: 1.1-1.5) (p < 0.001). The SMR decreased with advancing age, and the mortality rate was highest for men with humerus fractures.
In men, the risk of death related to proximal humerus fracture was even higher than that reported previously for hip fracture. Compared to the general population, the SMR was double for humerus fracture patients, whereas wrist fracture had no effect on mortality.
髋部骨折后死亡率增加已有充分记录。尽管上肢骨折是常见损伤,但上肢骨折住院后的死亡率尚不清楚。在此,我们确定了年龄≥16岁的上肢骨折患者住院后的死亡率。
我们收集了2002年至2008年间入住芬兰中部医院创伤病房的5985例患者的诊断代码(ICD10)、手术代码(NOMESCO)以及7项其他特征的数据。在研究期间,929名女性和753名男性发生了上肢骨折。对患者进行随访直至2012年底。使用风险人群数据计算死亡率。
到随访结束时(平均持续时间6年),179名女性(19%)和105名男性(14%)死亡。所有患者的标准化死亡率(SMR)为1.5(95%CI:1.4 - 1.7)。男性的SMR(2.1,CI:1.7 - 2.5)高于女性(1.3,CI:1.1 - 1.5)(p < 0.001)。SMR随年龄增长而降低,肱骨骨折男性的死亡率最高。
在男性中,与近端肱骨骨折相关的死亡风险甚至高于先前报道的髋部骨折。与一般人群相比,肱骨骨折患者的SMR是两倍,而腕部骨折对死亡率没有影响。