Gomez-Tames Jose, Fukuhara Yuto, He Siyu, Saito Kazuyuki, Ito Koichi, Yu Wenwei
Medical System Engineering Department, Graduate School of Engineering, Chiba University, Yayoi Chou, Inage Ku, 1-33, Chiba 263-8522, Japan.
Medical System Engineering Department, Graduate School of Engineering, Chiba University, Yayoi Chou, Inage Ku, 1-33, Chiba 263-8522, Japan.
Comput Biol Med. 2015 Jun;61:144-9. doi: 10.1016/j.compbiomed.2015.03.029. Epub 2015 Apr 9.
Variation of the dielectric properties of tissues could happen due to aging, moisture of the skin, muscle denervation, and variation of blood flow by temperature. Several studies used burst-modulated alternating stimulation to improve activation and comfort by reducing tissue impedance as a possible mechanism to generate muscle activation with less energy. The study of the effect of dielectric properties of biological tissues in nerve activation presents a fundamental problem, which is the difficulty of systematically changing the morphological factors and dielectric properties of the subjects under study. We tackle this problem by using a simulation and an experimental study. The experimental study is a novel method that combines a fat tissue-equivalent phantom, with known and adjustable dielectric properties, with the human thigh. In this way, the dispersion of the tissue under study could be modified to observe its effects systematically in muscle activation. We observed that, to generate a given amount of muscle or nerve activation under conditions of decreased impedance, the magnitude of the current needs to be increased while the magnitude of the voltage needs to be decreased.
由于衰老、皮肤水分、肌肉去神经支配以及温度引起的血流变化，组织的介电特性可能会发生改变。一些研究使用脉冲调制交变刺激，通过降低组织阻抗来改善激活效果和舒适度，这可能是一种以较少能量产生肌肉激活的机制。对生物组织介电特性在神经激活中的作用的研究存在一个基本问题，即难以系统地改变研究对象的形态学因素和介电特性。我们通过模拟和实验研究来解决这个问题。实验研究是一种新颖的方法，它将具有已知且可调节介电特性的脂肪组织等效体模与人体大腿相结合。通过这种方式，可以改变被研究组织的弥散情况，以便系统地观察其在肌肉激活中的作用。我们观察到，在阻抗降低的条件下要产生给定程度的肌肉或神经激活，电流大小需要增加而电压大小需要降低。
