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[1985年至1988年中国的黑热病。卫生部寄生虫病咨询委员会]

[Kala-azar in China from 1985 to 1988. Advisory Committee on Parasitic Diseases, MOPH].

出版信息

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1989;7(3):161-2.

PMID:2591032
Abstract

A total of 1,069 newly discovered cases of kala-azar (a few recurrent cases included) is recorded in China during the four year period from 1985 to 1988. The kala-azar patients were found in the Provinces and Autonomous Regions of Gansu, Sichuan, Xinjiang, Shaanxi, Shanxi, Inner-Mongolia and Shandong. Comparing with the 443 cases recorded during the previous 4 years period 1981-1984, significant uprise of the disease is evident, especially in the Provinces of Gansu and Sichuan. In southern Gansu and northern Sichuan, the incidence of visceral leishmaniasis in dogs is consistently high and these places are considered as areas endemic to leishmaniasis of canine source. Phlebotomus chinensis naturally infected with promastigotes are found in the mountainous regions 2,200 m and 1,500 m above the sea level respectively, and the promastigotes are identified as Leishmania donovani. As kala-azar patients and dogs infected with visceral leishmaniasis are mostly in the area below 1,600 m sea level and the area above 2,000 m sea level is unpopulated, the natural infection of sandflies was thought, therefore, to come from wild animal hosts and the natural nidus of kala-azar there warrants further investigation. It is suggested that consolidation and surveillance should be emphasized in endemic areas where leishmaniasis control has been very successful and research projects encouraged to meet the technical need for further achievement.

摘要

1985年至1988年这四年间,中国共记录了1069例新发现的黑热病病例(包括少数复发病例)。黑热病患者分布在甘肃、四川、新疆、陕西、山西、内蒙古和山东等省、自治区。与1981年至1984年的前四年记录的443例相比,该病明显上升,尤其是在甘肃和四川省。在甘肃南部和四川北部,犬内脏利什曼病的发病率一直很高,这些地方被认为是犬源性利什曼病的流行地区。分别在海拔2200米和1500米的山区发现了自然感染前鞭毛体的中华白蛉,前鞭毛体被鉴定为杜氏利什曼原虫。由于黑热病患者和感染内脏利什曼病的犬大多在海拔1600米以下的地区,而海拔2000米以上的地区无人居住,因此认为白蛉的自然感染来自野生动物宿主,那里黑热病的自然疫源地值得进一步调查。建议在利什曼病防治工作非常成功的流行地区加强巩固和监测,并鼓励开展研究项目以满足进一步取得成果的技术需求。

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