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皮下植入式心脏除颤器用于透析患者:减少中心静脉狭窄和感染的策略。

Subcutaneous implantable cardioverter defibrillator for dialysis patients: a strategy to reduce central vein stenoses and infections.

机构信息

Rancho Los Amigos National Rehabilitation Center, Downey, CA.

Albany Medical College, Albany, NY.

出版信息

Am J Kidney Dis. 2015 Jul;66(1):154-8. doi: 10.1053/j.ajkd.2015.01.028. Epub 2015 Apr 22.

DOI:10.1053/j.ajkd.2015.01.028
PMID:25911316
Abstract

Central venous stenosis is a common complication of the transvenous leads associated with an implantable cardioverter defibrillator (ICD). Although epicardial leads have been reported to bypass this complication, their placement is much more invasive than the subcutaneous ICDs (SICDs) and requires the services of a cardiothoracic surgeon. Recent data have demonstrated successful defibrillation using an SICD. In this report, we present 4 long-term hemodialysis patients treated successfully with an SICD. 3 patients received the device for primary prevention of sudden cardiac death (cardiomyopathy with low ejection fraction). The patient in the fourth case had a prolonged QT interval and received the device for secondary prevention. 3 patients had an arteriovenous fistula, whereas 1 patient was dialyzing with a tunneled dialysis catheter. Insertion of an SICD is a minimally invasive procedure. By virtue of leaving the venous system untouched, this approach might offer the advantage of reduced risk of central venous stenosis and infection over an endocardial ICD with transvenous leads. SICD is not experimental; it has been approved by the US Food and Drug Administration and is currently being used in the United States and Europe.

摘要

中心静脉狭窄是与植入式心脏复律除颤器(ICD)相关的经静脉导线的常见并发症。虽然已经报道心外膜导线可以绕过这种并发症,但其放置比皮下 ICD(SICD)更具侵入性,并且需要心胸外科医生的服务。最近的数据表明,SICD 可成功进行除颤。在本报告中,我们介绍了 4 例长期血液透析患者成功接受了 SICD 治疗。3 例患者因原发性预防心源性猝死(射血分数低的心肌病)而接受该设备治疗。第 4 例患者的 QT 间期延长,接受该设备进行二级预防。3 例患者有动静脉瘘,而 1 例患者正在使用隧道透析导管进行透析。SICD 的插入是一种微创程序。由于不触及静脉系统,这种方法可能比经静脉导线的心内膜 ICD 具有更低的中心静脉狭窄和感染风险的优势。SICD 并非实验性的;它已获得美国食品和药物管理局的批准,目前正在美国和欧洲使用。

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