Craft J A, Alessandrini E, Kenney L B, Klein B, Bray G, Luban N L, Meek R, Nadkarni V M
Department of Pediatrics, Medical Center of Delaware, Newark 19718.
J Pediatr. 1994 Jan;124(1):93-5. doi: 10.1016/s0022-3476(94)70260-8.
Measurements of the saturation of arterial blood with oxygen (SaO2) were compared in 24 children during sickle cell crises. Simultaneous pulse oximetry (Nellcor N-100 pulse oximeter) and arterial blood analysis showed that SaO2 measured by pulse oximetry overestimated cooximeter-measured SaO2 (mean bias, 6.9%; p < 0.001). The blood gas machine-calculated SaO2 also overestimated cooximeter-measured SaO2 (p < 0.001). The bias increased with increasing age (p = 0.002) and carboxyhemoglobin level (p = 0.005) but was not related to methemoglobin, total hemoglobin, percentage of hemoglobin S, or percentage of hemoglobin F.
对24名镰状细胞危象患儿的动脉血氧饱和度(SaO2)测量值进行了比较。同时采用脉搏血氧饱和度测定法(Nellcor N - 100脉搏血氧饱和度仪)和动脉血分析,结果显示通过脉搏血氧饱和度测定法测得的SaO2高于经血气分析仪测定的SaO2(平均偏差为6.9%;p < 0.001)。血气分析仪计算得出的SaO2也高于经血气分析仪测定的SaO2(p < 0.001)。偏差随着年龄增长(p = 0.002)和碳氧血红蛋白水平升高(p = 0.005)而增加,但与高铁血红蛋白、总血红蛋白、血红蛋白S百分比或血红蛋白F百分比无关。