Springer Bryan D
OrthoCarolina Hip Knee Center, Charlotte, NC 28207.
J Arthroplasty. 2015 Jun;30(6):908-11. doi: 10.1016/j.arth.2015.03.042. Epub 2015 Apr 21.
Periprosthetic joint infection remains one of the most common failure modes following total hip and total knee arthroplasty. As such, a systematic and cost effective approach to the evaluation and work-up of a patient with a suspected periprosthetic joint infection should be undertaken in every patient with a painful total joint. Although we have many diagnostic tools, a history and physical remain the most important. Many of the current laboratory tests are indirect measure of infection, lack specificity for diagnosis of infection, but serve as sensitive and cost effective screening tools. In addition, a new definition of periprosthetic infection helps to standardize the diagnosis. Biomarkers hold the promise of improved specificity and are becoming increasingly popular as a diagnostic tool.
人工关节周围感染仍然是全髋关节和全膝关节置换术后最常见的失败模式之一。因此，对于每一位有疼痛的全关节患者，都应采取系统且具有成本效益的方法来评估和检查疑似人工关节周围感染的患者。尽管我们有许多诊断工具，但病史和体格检查仍然是最重要的。目前的许多实验室检查都是对感染的间接测量，缺乏感染诊断的特异性，但可作为敏感且具有成本效益的筛查工具。此外，人工关节周围感染的新定义有助于规范诊断。生物标志物有望提高特异性，并且作为一种诊断工具正变得越来越受欢迎。
