Bender S D, Dorfmann A D, Schulman J D, Bustillo M
Genetics & IVF Institute, Fairfax, Virginia 22031.
Fertil Steril. 1989 Dec;52(6):1070-1. doi: 10.1016/s0015-0282(16)53178-1.
A case is described in which a tetraploid and aneuploid conceptus resulted from dipronuclear embryos from in vitro fertilization. This finding strongly suggests that, after a meiotic error in either the egg or sperm, polyploidy has occurred as the result of a postfertilization mitotic error.
本文描述了一例体外受精来源的双原核胚胎发育为四倍体和非整倍体胎儿的病例。这一发现有力地表明,在卵子或精子发生减数分裂错误后,多倍体是受精后有丝分裂错误导致的结果。