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在不同种族/族裔的男男性行为年轻人群体中,暴露前预防(PrEP)的接受情况:P18研究

Acceptability of PrEP Uptake Among Racially/Ethnically Diverse Young Men Who Have Sex With Men: The P18 Study.

作者信息

Pérez-Figueroa Rafael E, Kapadia Farzana, Barton Staci C, Eddy Jessica A, Halkitis Perry N

出版信息

AIDS Educ Prev. 2015 Apr;27(2):112-25. doi: 10.1521/aeap.2015.27.2.112.

DOI:10.1521/aeap.2015.27.2.112
PMID:25915697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4550097/
Abstract

Pre-exposure prophylaxis (PrEP) is considered an effective biomedical approach for HIV prevention. However, there is limited understanding of PrEP uptake among racially/ethnically and socioeconomically diverse young men who have sex with men (YMSM). This study examined attitudes and perceptions toward PrEP uptake among YMSM by conducting semistructured interviews with a sample (N = 100) of YMSM in New York City. Thematic analysis was employed to explore key issues related to attitudes and perceptions toward PrEP utilization. Findings suggest that self-perceived risk for HIV transmission, enjoying unprotected sex, and being in a romantic relationship were associated with PrEP uptake. The most prominent barriers to PrEP uptake included costs, adherence regimen, and access. In summary, these findings underscore the importance of addressing behavioral and structural factors in maximizing the effectiveness of PrEP. In addition, PrEP implementation programs ought to consider the role of social and structural challenges to PrEP uptake and adherence among YMSM.

摘要

暴露前预防(PrEP)被认为是预防艾滋病毒的一种有效生物医学方法。然而,对于不同种族/族裔和社会经济背景的男男性行为者(YMSM)中PrEP的接受情况了解有限。本研究通过对纽约市100名YMSM样本进行半结构化访谈,调查了YMSM对PrEP接受情况的态度和看法。采用主题分析法探讨与PrEP使用态度和看法相关的关键问题。研究结果表明,自我感知的艾滋病毒传播风险、享受无保护性行为以及处于恋爱关系与PrEP的接受情况有关。PrEP接受的最突出障碍包括成本、依从方案和获取途径。总之,这些发现强调了在最大化PrEP有效性方面解决行为和结构因素的重要性。此外,PrEP实施项目应考虑社会和结构挑战对YMSM中PrEP接受和依从的作用。

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Interim guidance for clinicians considering the use of preexposure prophylaxis for the prevention of HIV infection in heterosexually active adults.临床医生考虑在异性性行为活跃的成年人中使用暴露前预防以预防 HIV 感染的临时指南。
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