Ogbera A O, Kapur A, Odeyemi K, Longe-Peters K, Adeyeye O O, Odeniyi I, Ogunnowo B E
J Prev Med Hyg. 2014 Jun;55(2):42-5.
Nigeria is a country saddled with a high tuberculosis (TB) and human immunodeficiency virus (HIV) burden but the possible combination of these communicable diseases with diabetes mellitus (DM) has been overlooked. We undertook to determine the burden of HIV and DM in persons with TB by documenting the prevalence rates of these disorders.
This is a cross-sectional Study that was conducted within 54TB/DOT centers in Lagos State. A total of 3,376 persons with TB who were on antiTB drugs were screened for HIV and DM using standardized tests. Statistical analysis was performed using Students t test and chi square.
The frequency of occurrence of DM in TB and that of HIV in TB were comparable (4.8% Vs 3.5%). The Study subjects with DM were older, had higher waist circumference measurements and had higher proportions of hypertension compared to the subjects without DM. The combination of HIV and DM in TB was found in (0.3%). We also noted that DM in TB and HIV in TB occurred more frequently in the third and fourth decades of life.
This study demonstrated the potential co existence of HIV, DM and Tuberculosis. It is therefore important that these two diseases are sought for in patients with TB considering the changing epidemiology of these diseases particularly in developing countries like Nigeria.
尼日利亚是一个结核病（TB）和人类免疫缺陷病毒（HIV）负担沉重的国家，但这些传染病与糖尿病（DM）可能的合并情况一直被忽视。我们通过记录这些疾病的患病率来确定结核病患者中HIV和DM的负担。
这是一项在拉各斯州54个结核病/直接观察治疗中心开展的横断面研究。使用标准化检测方法，对总共3376名正在接受抗结核药物治疗的结核病患者进行了HIV和DM筛查。采用学生t检验和卡方检验进行统计分析。
结核病患者中DM的发生率与HIV的发生率相当（4.8%对3.5%）。与无DM患者相比，患有DM的研究对象年龄更大，腰围测量值更高，高血压比例更高。结核病患者中HIV与DM合并存在的情况占（0.3%）。我们还注意到，结核病患者中的DM和HIV在生命的第三个和第四个十年中更为常见。
本研究证明了HIV、DM和结核病可能并存。因此，鉴于这些疾病不断变化的流行病学情况，特别是在尼日利亚这样的发展中国家，在结核病患者中筛查这两种疾病非常重要。
