工作场所空气中氯丙烯的溶剂解吸气相色谱测定法

[Solvent desorption gas chromatography for determination of allyl chloride in workplace atmosphere].

作者信息

Li Xiaojuan, Zhu Baoli, Wu Jian

机构信息

Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China.

Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China. E-mail:

出版信息

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2015 Feb;33(2):141-3.

PMID:25916371

Abstract

OBJECTIVE

To establish a method for determination of allyl chloride in the workplace atmosphere by solvent desorption-capillary column gas chromatography.

METHODS

Allyl chloride in the atmosphere was adsorbed by activated charcoal tubes and desorbed using dichloromethane, and was then separated by capillary column gas chromatography and determined by flame ionization detector.

RESULTS

The concentration of allyl chloride showed a good linear relationship within the range of 0∼200 µg/ml. The linear regression equation was y = 1.27x-0.22 with the correlation coefficient r being 0.999 8. The limit of detection was 0.20 µg /mL. If 7.5 L of air was sampled, the minimum detectable concentration was 0.03 mg/m³. The intra-day and inter-day relative standard deviations (RSD) of repetitive measurement at the high, middle, and low concentration levels were 2.7%∼4.8%. The average sampling efficiency was 100%. The overall desorption efficiency was 94.4%. The breakthrough volume was over 0.59 mg (100 mg activated charcoal).

CONCLUSION

The method applies to the determination of allyl chloride in the workplace atmosphere.

摘要

目的

建立溶剂解吸-毛细管柱气相色谱法测定工作场所空气中氯丙烯的方法。

方法

空气中氯丙烯用活性炭管采集，二氯甲烷解吸后，经毛细管柱气相色谱分离，用氢火焰离子化检测器测定。

结果

氯丙烯浓度在0～200μg/ml范围内线性关系良好，线性回归方程为y = 1.27x - 0.22，相关系数r为0.999 8。检出限为0.20μg/mL。若采集7.5L空气，最低检出浓度为0.03mg/m³。高、中、低浓度水平重复测定的日内和日间相对标准偏差（RSD）为2.7%～4.8%。平均采样效率为100%。总解吸效率为94.4%。穿透容量超过0.59mg（100mg活性炭）。