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本文引用的文献

1
'These nodding people': Experiences of having a child with nodding syndrome in postconflict Northern Uganda.“这些点头的人”:乌干达北部冲突后生育患有点头综合征孩子的经历
Epilepsy Behav. 2015 Jan;42:71-7. doi: 10.1016/j.yebeh.2014.10.027. Epub 2014 Dec 11.
2
Patients with nodding syndrome in Uganda improve with symptomatic treatment: a cross-sectional study.乌干达点头综合征患者经对症治疗后病情改善:一项横断面研究。
BMJ Open. 2014 Nov 14;4(11):e006476. doi: 10.1136/bmjopen-2014-006476.
3
Nodding syndrome since 2012: recent progress, challenges and recommendations for future research.2012年以来的点头综合征:近期进展、挑战及未来研究建议
Trop Med Int Health. 2015 Feb;20(2):194-200. doi: 10.1111/tmi.12421. Epub 2014 Nov 19.
4
Valproic acid and fatalities in children: a review of individual case safety reports in VigiBase.丙戊酸与儿童死亡:VigiBase中个体病例安全报告综述
PLoS One. 2014 Oct 10;9(10):e108970. doi: 10.1371/journal.pone.0108970. eCollection 2014.
5
Nodding syndrome-a new hypothesis and new direction for research.点头综合征——一种新假说与新研究方向
Int J Infect Dis. 2014 Oct;27:74-7. doi: 10.1016/j.ijid.2014.08.001. Epub 2014 Aug 23.
6
A longitudinal study on nodding syndrome--a new African epilepsy disorder.点头综合征的纵向研究——一种新的非洲癫痫疾病。
Epilepsia. 2014 Jan;55(1):86-93. doi: 10.1111/epi.12483. Epub 2013 Dec 20.
7
Proposed guidelines for the management of nodding syndrome.点头综合征管理的拟议指南。
Afr Health Sci. 2013 Jun;13(2):219-32. doi: 10.4314/ahs.v13i2.4.
8
Nodding syndrome in Mundri county, South Sudan: environmental, nutritional and infectious factors.南苏丹蒙德里县的点头综合征:环境、营养和感染因素
Afr Health Sci. 2013 Jun;13(2):183-204. doi: 10.4314/ahs.v13i2.2.
9
Nodding syndrome.点头症。
Emerg Infect Dis. 2013;19(9):1374-84. doi: 10.3201/eid1909.130401.
10
An Epidemiologic Investigation of Potential Risk Factors for Nodding Syndrome in Kitgum District, Uganda.乌干达基特古姆区点头综合征潜在风险因素的流行病学调查
PLoS One. 2013 Jun 18;8(6):e66419. doi: 10.1371/journal.pone.0066419. Print 2013.

1994年,乌干达西部,点头综合征。

Nodding syndrome, western Uganda, 1994.

作者信息

Kaiser Christoph, Rubaale Tom, Tukesiga Ephraim, Kipp Walter, Asaba George

机构信息

Basic Health Services, Kabarole and Bundibugyo Districts, Fort Portal, Uganda; Vector Control Unit, Ministry of Health, Fort Portal, Uganda; Department of Public Health Sciences, University of Alberta, Edmonton, Canada

Basic Health Services, Kabarole and Bundibugyo Districts, Fort Portal, Uganda; Vector Control Unit, Ministry of Health, Fort Portal, Uganda; Department of Public Health Sciences, University of Alberta, Edmonton, Canada.

出版信息

Am J Trop Med Hyg. 2015 Jul;93(1):198-202. doi: 10.4269/ajtmh.14-0838. Epub 2015 Apr 27.

DOI:10.4269/ajtmh.14-0838
PMID:25918208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4497897/
Abstract

Nodding syndrome (NS) is a poorly understood condition, which was delineated in 2008 as a new epilepsy syndrome. So far, confirmed cases of NS have been observed in three circumscribed African areas: southern Tanzania, southern Sudan, and northern Uganda. Case-control studies have provided evidence of an association between NS and infection with Onchocerca volvulus, but the causation of NS is still not fully clarified. We report a case of a 15-year old boy with head nodding seizures and other characteristic features of NS from an onchocerciasis endemic area in western Uganda, with no contiguity to the hitherto known areas. We suggest that the existence of NS should be systematically investigated in other areas.

摘要

点头综合征(NS)是一种了解甚少的病症,于2008年被划定为一种新的癫痫综合征。迄今为止,已在非洲三个限定区域观察到确诊的点头综合征病例:坦桑尼亚南部、苏丹南部和乌干达北部。病例对照研究已提供证据表明点头综合征与盘尾丝虫感染之间存在关联,但点头综合征的病因仍未完全阐明。我们报告了一例来自乌干达西部盘尾丝虫病流行区的15岁男孩,他患有点头癫痫发作及点头综合征的其他特征性表现,且与迄今已知区域并无接壤。我们建议应在其他地区对点头综合征的存在情况进行系统调查。