Kaiser Christoph, Rubaale Tom, Tukesiga Ephraim, Kipp Walter, Asaba George
Basic Health Services, Kabarole and Bundibugyo Districts, Fort Portal, Uganda; Vector Control Unit, Ministry of Health, Fort Portal, Uganda; Department of Public Health Sciences, University of Alberta, Edmonton, Canada
Basic Health Services, Kabarole and Bundibugyo Districts, Fort Portal, Uganda; Vector Control Unit, Ministry of Health, Fort Portal, Uganda; Department of Public Health Sciences, University of Alberta, Edmonton, Canada.
Am J Trop Med Hyg. 2015 Jul;93(1):198-202. doi: 10.4269/ajtmh.14-0838. Epub 2015 Apr 27.
Nodding syndrome (NS) is a poorly understood condition, which was delineated in 2008 as a new epilepsy syndrome. So far, confirmed cases of NS have been observed in three circumscribed African areas: southern Tanzania, southern Sudan, and northern Uganda. Case-control studies have provided evidence of an association between NS and infection with Onchocerca volvulus, but the causation of NS is still not fully clarified. We report a case of a 15-year old boy with head nodding seizures and other characteristic features of NS from an onchocerciasis endemic area in western Uganda, with no contiguity to the hitherto known areas. We suggest that the existence of NS should be systematically investigated in other areas.
点头综合征(NS)是一种了解甚少的病症,于2008年被划定为一种新的癫痫综合征。迄今为止,已在非洲三个限定区域观察到确诊的点头综合征病例:坦桑尼亚南部、苏丹南部和乌干达北部。病例对照研究已提供证据表明点头综合征与盘尾丝虫感染之间存在关联,但点头综合征的病因仍未完全阐明。我们报告了一例来自乌干达西部盘尾丝虫病流行区的15岁男孩,他患有点头癫痫发作及点头综合征的其他特征性表现,且与迄今已知区域并无接壤。我们建议应在其他地区对点头综合征的存在情况进行系统调查。