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对并发物质使用障碍和边缘型人格障碍的干预措施的系统评价。

A systematic review of interventions for co-occurring substance use and borderline personality disorders.

作者信息

Lee Nicole K, Cameron Jacqui, Jenner Linda

机构信息

LeeJenn Health Consultants, Melbourne, Australia.

National Centre for Education and Training on Addiction, Flinders University, Adelaide, Australia.

出版信息

Drug Alcohol Rev. 2015 Nov;34(6):663-72. doi: 10.1111/dar.12267. Epub 2015 Apr 28.

Abstract

ISSUES

The aim of this study was to undertake a systematic review on effective treatment options for co-occurring substance use and borderline personality disorders to examine effective treatments for this group.

APPROACH

A systematic review using a narrative analysis approach was undertaken as there were too few studies within each intervention type to undertake a meta-analysis. The inclusion criteria comprised of English language studies (between 1999 and 2014) and a sample of >70% borderline personality disorder, with measurable outcomes for substance use and borderline personality disorder. All abstracts were screened (n = 376) resulting in 49 studies assessed for eligibility, with 10 studies, examining three different treatment types, included in the final review.

KEY FINDINGS

There were four studies that examined dialectical behaviour therapy (DBT), three studies that examined dynamic deconstructive psychotherapy (DDP) and three studies that examined dual-focused schema therapy (DFST). Both DBT and DDP demonstrated reductions in substance use, suicidal/self-harm behaviours and improved treatment retention. DBT also improved global and social functioning. DFST reduced substance use and both DFST and DPP improved treatment utilisation, but no other significant positive changes were noted.

IMPLICATIONS

Overall, there were a small number of studies with small sample sizes, so further research is required. However, in the absence of a strong evidence base, there is a critical need to respond to this group with co-occurring borderline personality disorder and substance use.

CONCLUSION

Both DBT and DPP showed some benefit in reducing symptoms, with DBT the preferred option given its superior evidence base with women in particular.

摘要

问题

本研究的目的是对同时存在物质使用障碍和边缘型人格障碍的有效治疗方案进行系统评价,以检验针对该群体的有效治疗方法。

方法

由于每种干预类型的研究数量过少,无法进行荟萃分析,因此采用叙述性分析方法进行系统评价。纳入标准包括1999年至2014年期间的英文研究,以及边缘型人格障碍样本比例超过70%,且有物质使用障碍和边缘型人格障碍的可测量结果。对所有摘要进行筛选(n = 376),最终有49项研究被评估是否符合纳入标准,其中10项研究,检验了三种不同的治疗类型,被纳入最终评价。

主要发现

有四项研究检验了辩证行为疗法(DBT),三项研究检验了动态解构心理疗法(DDP),三项研究检验了双焦点图式疗法(DFST)。DBT和DDP均显示物质使用减少、自杀/自伤行为减少,治疗保留率提高。DBT还改善了整体和社会功能。DFST减少了物质使用,DFST和DPP均提高了治疗利用率,但未观察到其他显著的积极变化。

启示

总体而言,研究数量较少且样本量小,因此需要进一步研究。然而,在缺乏有力证据基础的情况下,迫切需要对同时存在边缘型人格障碍和物质使用障碍的群体做出应对。

结论

DBT和DPP在减轻症状方面均显示出一定益处,鉴于DBT尤其是对女性有更充分的证据基础,它是首选方案。

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