Bastidas-L Andrea Carolina, Colina-Chourio José A, Guevara Jesnel M, Nunez Alexis
Invest Clin. 2015 Mar;56(1):25-32.
The objective of this investigation was to evaluate gas exchange and cardiopulmonary functional behavior in patients with pulmonary hypertension (PH) before, during and after the change to a prone position. Thirty patients with PH and alterations in gas exchange were included in the study. Gas exchange measurements were performed in four stages: at the baseline supine position and after 30, 120 and 240 minutes in prone position. Also, the patients were evaluated by the six minutes walking test (6MWT) after 30 days in prone position during night's sleep. After four hours in prone position, all patients showed an increase of PaO2 and arterial saturation of oxygen (SaO2), with a decrease of intrapulmonary shunts, improving the gas exchange and therefore the physiological demand imposed by exercise in patients with PH.
本研究的目的是评估肺动脉高压（PH）患者在转为俯卧位之前、期间和之后的气体交换及心肺功能行为。30例有气体交换改变的PH患者纳入研究。气体交换测量分四个阶段进行：在基线仰卧位时以及俯卧位30分钟、120分钟和240分钟后。此外，在夜间睡眠中俯卧位30天后，通过六分钟步行试验（6MWT）对患者进行评估。俯卧位四小时后，所有患者的动脉血氧分压（PaO2）和动脉血氧饱和度（SaO2）均升高，肺内分流减少，气体交换得到改善，从而改善了PH患者运动时的生理需求。
