Arikan Inci, Namdar Nazli Dizen, Kahraman Cuneyt, Dagci Merve, Ece Ezgi
Department of Public Health, Medical Faculty, Dumlupinar University, Kutahya, Turkey E-mail :
Asian Pac J Cancer Prev. 2015;16(8):3183-8. doi: 10.7314/apjcp.2015.16.8.3183.
This study aimed to evaluate the prevalence of skin lesions, which is a health effect of chronic arsenic (As) exposure, and determine the hair/blood arsenic concentrations of people living in Kutahya villages who are using and drinking tap water with a high concentration of arsenic.
A total of 303 people were included in the present cross-sectional study. A prepared questionnaire form was used to collect the participants' information and environmental history. Skin examination was performed on all participants. Hair, blood and water samples were analyzed using atomic absorption spectroscopy. The cumulative arsenic index (CAI) was calculated for all participants.
Villages were divided into two groups according to the arsenic level (<20 μg/L, Group I; >20 μg/L, Group II) in their water. The prevalence of skin lesions, hair and blood arsenic level, and CAI were found to be higher in the Group II participants. There was a positive association between body arsenic levels and CAI in the participants of each group.
The number of skin lesions and arsenic concentrations in body samples were found to increase with the water arsenic level and exposure time. We hope that sharing this study's results with local administrators will help accelerate the rehabilitation of water sources in Kutahya.
本研究旨在评估慢性砷暴露对健康产生影响的皮肤病变患病率,并测定库塔亚地区饮用高砷浓度自来水居民的头发/血液砷浓度。
本横断面研究共纳入303人。使用预先准备好的问卷收集参与者的信息和环境史。对所有参与者进行皮肤检查。采用原子吸收光谱法分析头发、血液和水样。计算所有参与者的累积砷指数(CAI)。
根据水中砷水平(<20μg/L,第一组;>20μg/L,第二组)将村庄分为两组。发现第二组参与者的皮肤病变患病率、头发和血液砷水平以及CAI更高。每组参与者的体内砷水平与CAI之间存在正相关。
发现皮肤病变数量和体内样本中的砷浓度随水中砷水平和暴露时间增加。我们希望与当地管理人员分享本研究结果将有助于加速库塔亚地区水源的修复。