自闭症儿童血清25-羟维生素D（25-OHD）水平较低。
Low serum levels of 25-hydroxyvitamin D (25-OHD) in children with autism.
作者信息
Tostes Márcia Helena Fávero de Souza, Polonini Hudson Caetano, Gattaz Wagner Farid, Raposo Nádia Rezende Barbosa, Baptista Edilene Bolutari
机构信息
Núcleo de Pesquisa e Inovação em Ciências da Saúde, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, MG, Brazil.
Núcleo de Pesquisa e Inovação em Ciências da Saúde, UFJF.
出版信息
Trends Psychiatry Psychother. 2012 Sep;34(3):161-3. doi: 10.1590/s2237-60892012000300008.
OBJECTIVE
To confirm previous evidence suggesting an association between autism and low vitamin D serum levels.
METHODS
This preliminary exploratory study assessed the circulating levels of 25-hydroxyvitamin D (25-OHD) in pediatric patients with autism and in typically developing controls from Juiz de Fora, Brazil.
RESULTS
Serum levels of 25-OHD were lower in children with autism (26.48 ± 3.48 ng mL-1) when compared to typically developing subjects (40.52 ± 3.13 ng mL-1) (p < 0.001).
CONCLUSION
Our findings attest to the importance of vitamin supplementation during pregnancy and in the treatment of children with autism, who tend to present low vitamin D consumption rates.
目的
证实先前表明自闭症与低血清维生素D水平之间存在关联的证据。
方法
这项初步探索性研究评估了巴西茹伊斯迪福拉市自闭症儿科患者和发育正常的对照组中25-羟基维生素D（25-OHD）的循环水平。
结果
与发育正常的受试者（40.52±3.13 ng/mL）相比，自闭症儿童的血清25-OHD水平较低（26.48±3.48 ng/mL）（p<0.001）。
结论
我们的研究结果证明了孕期补充维生素以及治疗自闭症儿童的重要性，因为自闭症儿童往往维生素D摄入量较低。
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