Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, MSC 226, Charleston, SC, 29425, USA.
Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Eur Radiol. 2015 Dec;25(12):3560-6. doi: 10.1007/s00330-015-3767-3. Epub 2015 Apr 30.
To evaluate the accuracy, reliability and time saving potential of a novel cardiac CT (CCT)-based, automated software for the assessment of segmental left ventricular function compared to visual and manual quantitative assessment of CCT and cardiac magnetic resonance (CMR).
Forty-seven patients with suspected or known coronary artery disease (CAD) were enrolled in the study. Wall thickening was calculated. Segmental LV wall motion was automatically calculated and shown as a colour-coded polar map. Processing time for each method was recorded.
Mean wall thickness in both systolic and diastolic phases on polar map, CCT, and CMR was 9.2 ± 0.1 mm and 14.9 ± 0.2 mm, 8.9 ± 0.1 mm and 14.5 ± 0.1 mm, 8.3 ± 0.1 mm and 13.6 ± 0.1 mm, respectively. Mean wall thickening was 68.4 ± 1.5 %, 64.8 ± 1.4 % and 67.1 ± 1.4 %, respectively. Agreement for the assessment of LV wall motion between CCT, CMR and polar maps was good. Bland-Altman plots and ICC indicated good agreement between CCT, CMR and automated polar maps of the diastolic and systolic segmental wall thickness and thickening. The processing time using polar map was significantly decreased compared with CCT and CMR.
Automated evaluation of segmental LV function with polar maps provides similar measurements to manual CCT and CMR evaluation, albeit with substantially reduced analysis time.
• Cardiac computed tomography (CCT) can accurately assess segmental left ventricular wall function. • A novel automated software permits accurate and fast evaluation of wall function. • The software may improve the clinical implementation of segmental functional analysis.
评估一种新型基于心脏 CT（CCT）的自动软件评估节段性左心室功能的准确性、可靠性和节省时间的潜力，与 CCT 和心脏磁共振（CMR）的视觉和手动定量评估相比。
研究纳入了 47 名疑似或已知冠心病（CAD）患者。计算了壁增厚。自动计算节段性 LV 壁运动，并以彩色编码极地图显示。记录每种方法的处理时间。
极地图、CCT 和 CMR 上收缩期和舒张期的平均壁厚度分别为 9.2±0.1mm 和 14.9±0.2mm、8.9±0.1mm 和 14.5±0.1mm、8.3±0.1mm 和 13.6±0.1mm。平均壁增厚率分别为 68.4±1.5%、64.8±1.4%和 67.1±1.4%。CCT、CMR 和极地图评估 LV 壁运动的一致性良好。Bland-Altman 图和 ICC 表明，CCT、CMR 和自动极地图的舒张期和收缩期节段壁厚度和增厚率之间具有良好的一致性。与 CCT 和 CMR 相比，使用极地图的处理时间显著减少。
极地图自动评估节段性 LV 功能可提供与手动 CCT 和 CMR 评估相似的测量值，尽管分析时间大大减少。
• 心脏计算机断层扫描（CCT）可准确评估节段性左心室壁功能。• 一种新型的自动软件可实现壁功能的准确和快速评估。• 该软件可能会改善节段性功能分析的临床实施。
