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亚美尼亚格加尔库尼克省糖尿病视网膜病变的患病率及主要相关危险因素:横断面研究

The prevalence of and major risk factors associated with diabetic retinopathy in Gegharkunik province of Armenia: cross-sectional study.

作者信息

Giloyan Aida, Harutyunyan Tsovinar, Petrosyan Varduhi

机构信息

Garo Meghrigian Institute for Preventive Ophthalmology, School of Public Health, American University of Armenia, 40 Marshal Baghramian Ave., Yerevan, 0019, Armenia.

School of Public Health, American University of Armenia, 40 Marshal Baghramian Ave., Yerevan, 0019, Armenia.

出版信息

BMC Ophthalmol. 2015 Apr 30;15:46. doi: 10.1186/s12886-015-0032-0.

Abstract

BACKGROUND

Diabetic retinopathy (DR) is one of the leading causes of blindness in adults in industrialized countries and the emerging cause of blindness in developing countries. The objective of this study was to describe the prevalence of DR and risk factors associated with it among diabetic patients.

METHODS

The analytical cross-sectional survey and eye screenings were carried out among 625 diabetic patients from urban and rural areas of Gegharkunik region. DR was assessed by dilated ophthalmoscopy and defined based on the WHO International Classification of Diseases. The survey instrument, included questions about demographics, disease history, health status, medication use and healthy lifestyle. Descriptive statistics and logistic regression were used to analyze the data.

RESULTS

The prevalence of DR in the sample was 36.2%. A total of 90.2% of patients with DR had non-proliferative, while 9.8% had proliferative DR. In bivariate analysis, age, diabetes duration, being under insulin treatment, blood glucose level, having non-communicable diseases were significantly associated with DR. In the adjusted analysis being under insulin treatment (OR = 3.24; 95% CI: 1.56-6.75), diabetes duration (OR = 1.23; 95% CI: 1.16-1.31) and age (OR = 1.05; 95% CI: 1.02-1.08) were independently associated with DR.

CONCLUSION

Earlier diagnosis of diabetes and DR can help to control some of these factors and prevent further complications and vision loss. Population-based educational programs on diabetes and diabetic retinopathy and continuous medical education on diabetes management can improve diabetes care and self-management and prevent eye complications.

摘要

背景

糖尿病视网膜病变(DR)是工业化国家成年人失明的主要原因之一,也是发展中国家失明的新兴原因。本研究的目的是描述糖尿病患者中DR的患病率及其相关危险因素。

方法

对来自格加尔库尼克地区城乡的625名糖尿病患者进行了分析性横断面调查和眼部筛查。通过散瞳眼底镜检查评估DR,并根据世界卫生组织国际疾病分类进行定义。调查工具包括有关人口统计学、病史、健康状况、药物使用和健康生活方式的问题。使用描述性统计和逻辑回归分析数据。

结果

样本中DR的患病率为36.2%。共有90.2%的DR患者患有非增殖性DR,而9.8%患有增殖性DR。在双变量分析中,年龄、糖尿病病程、接受胰岛素治疗、血糖水平、患有非传染性疾病与DR显著相关。在调整分析中,接受胰岛素治疗(OR = 3.24;95% CI:1.56 - 6.75)、糖尿病病程(OR = 1.23;95% CI:1.16 - 1.31)和年龄(OR = 1.05;95% CI:1.02 - 1.08)与DR独立相关。

结论

早期诊断糖尿病和DR有助于控制其中一些因素,预防进一步的并发症和视力丧失。基于人群的糖尿病和糖尿病视网膜病变教育项目以及糖尿病管理的持续医学教育可以改善糖尿病护理和自我管理,预防眼部并发症。

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